We studied the analgesic efficacy of tramadol 2 mg kg(-1) for post-operative analgesia after day-case adenoidectomy in children aged 1-3 yr. Eighty children were allocated randomly to receive tramadol 2 mg kg(-1) i.v. or placebo immediately after induction of anaesthesia. Anaesthesia was induced with alfentanil 10 microg kg(-1) and propofol 4 mg kg(-1) followed by mivacurium 0.2 mg kg(-1) for t...

BACKGROUND AND AIMS Local infiltration of the surgical wound is one of the important components of multimodal analgesia for post-operative pain relief. This study determines the post-operative analgesic effect of addition of dexmedetomidine to bupivacaine for local infiltration of the surgical wound. METHODS Sixty women belonging to American Society of Anesthesiologists' Grade 1 or 2 posted f...

The aim of this study was to investigate the effect of the μ-opioid receptor gene (OPRM1) A118G polymorphism on the requirement for post-operative fentanyl analgesia in patients undergoing radical gastrectomy. One hundred and twenty-eight gastric cancer patients scheduled to undergo radical gastrectomy under general anesthesia were enrolled in the study. Post-operative, patient-controlled intra...

sepsis and septic shock are among mortality causes following major surgeries. the charlson co-morbidity index consists of 19 weighted categories related to chronic health which measures the burden of co-morbidity. the goal of this study was to determine the incidence of postoperative sepsis in patients underwent gynecological and gastrointestinal cancer surgeries and predictive role of charlson...

Objectives: Alpha-2-receptor agonist has been used as an additive to local anaesthetics for various regional anaesthetic techniques. We compared clonidine and dexmedetomidine as an adjuvant to local anaesthetic agent in ultrasound guided axillary brachial plexus block with respect to hemodynamic parameters, onset and duration of sensory, motor block and duration of analgesia. Methods: Ultrasoun...

BACKGROUND The main advantages of video assisted thoracoscopic surgery (VATS) include less post-operative pain, rapid recovery, less postoperative complications, shorter hospital stay and early discharge. Although pain intensity is less as compared to conventional thoracotomy but still patients experience upto moderate pain postoperatively. The objective of this study was to assess the efficacy...

OBJECTIVE To test the effect of cognitive interventions with information given pre-operatively on post-operative outcomes in Chinese women undergoing elective hysterectomies. DESIGN An experimental design. The experimental group (n=48) received cognitive distraction and cognitive reappraisal with information, the control group (n=48) received information only. OUTCOME MEASURES Post-operativ...

Objective: The objective of the study was to compare effects dexmedetomidine versus midazolam-fentanyl on post-operative recovery, sedation, analgesia, and hemodynamic parameters in patients undergoing middle ear surgery under local anesthesia. Methods: Seventy-two were randomly divided into two equal groups - Group D (dexmedetomidine) MF (midazolam fentanyl). Intra operative heart rate, mean b...

Catheters were inserted into the extradural space under direct vision at the time of surgery for prolapsed intervertebral disc or lumbar canal stenosis. In the post-operative period, diamorphine (3 mg in 5 ml water) was injected through the catheter when patients requested analgesia. In only four of 49 patients was significant pain relief not achieved after extradural diamorphine injection. In ...