In cirrhosis, hepatic venous pressure gradient is used to measure portal venous and sinusoidal pressures, as well as drug-induced decreases of elevated pressures. The aim of this study was to investigate the influence of hepatic arterial flow (HAF) changes on portal venous perfusion (PVPP) and wedged hepatic venous pressure (WHVP). Normal and CCl4-cirrhotic rats were subjected to a bivascular l...

Anaphylactic shock is sometimes life-threatening, and it is accompanied by hepatic venoconstriction in animals, which, in part, accounts for anaphylactic hypotension. Roles of norepinephrine and α-adrenoceptor in anaphylaxis-induced hypotension and portal hypertension were investigated in anesthetized ovalbumin-sensitized Sprague-Dawley rats. The sensitized rats were randomly allocated to the f...

introduction: finding the probable governing pattern of peep and cvp changes is an area of interest for in-charge physicians and researchers. therefore, the present study was designed with the aim of evaluating the relationship between the mentioned pressures. methods: in this quasi-experimental study, patients under mechanical ventilation were evaluated with the aim of assessing the effect of ...

Portal biliopathy is defined as abnormalities in the extra- and intrahepatic ducts and gallbladder of patients with portal hypertension. This condition is associated with extrahepatic venous obstruction and dilatation of the venous plexus of the common bile duct, resulting in mural irregularities and compression of the biliary tree. Most patients with portal biliopathy remain asymptomatic, but ...

1 The hepatic portal vein of the anesthetized dog was cannulated and perfused with blood derived from the cannulated superior mesenteric vein. 2 The portal vein was perfused at constant flow, the hepatic portal venous pressure being monitored continuously together with the inferior vena caval pressure. From these measurements, the hepatic portal venous vascular resistance was calculated. 3 Nora...

conclusions in our study, portal venous thrombosis was detected in the patient who died during the acute period only. a study including large numbers of budd-chiari-syndrome patients with behcet’s disease and portal venous thrombosis would be helpful to determine the prognostic significance of portal venous thrombosis in budd-chiari-syndrome patients with behcet’s disease. in addition, patients...

Stenosis of either the portal or splenic vein increases splenic afferent nerve activity (SANA), which, through the splenorenal reflex, reduces renal blood flow. Because these maneuvers not only raise splenic venous pressure but also reduce splenic venous outflow, the question remained as to whether it is increased intrasplenic postcapillary pressure and/or reduced intrasplenic blood flow, which...

POSTERIOR PITUITARY EXTRACT is known to lower the portal venous pressure in animalsl-3 and in man a similar effect has been demonstrated during the control of bleeding from esophageal varices with intravenous pitressin.44 It has been suggested that pitressin lowers portal pressure by increasing splanchnic resistance.7 The present communication concerns the effects of intravenous pitressin on sp...

Endothelin is a vasoconstrictor peptide which has recently been isolated and sequenced from the vascular endothelial cells. It was reported to increase blood pressure in vivo and produce a prolonged contraction with a slow onset in vitro. The purpose of this study was to investigate whether endothelin can lower the portal pressure as another endogenous vasoconstriction peptidevasopressin (AVP) ...

BACKGROUND Hemodynamics during anaphylactic shock remain unclear. We determined hepatic and splanchnic responses to anaphylactic hypotension, compared with hemorrhage or sodium nitroprusside (SNP)-induced hypotension, in anesthetized rats. MATERIALS AND METHODS Portal pressure, systemic arterial pressure (SAP), central venous pressure, portal and hepatic arterial blood flow were measured. Spl...