نتایج جستجو برای: polyposis
تعداد نتایج: 11192 فیلتر نتایج به سال:
BACKGROUND MUTYH-associated polyposis is a recessively inherited disorder characterized by a lifetime risk of colorectal cancer that is up to 100%. Because specific histological and molecular genetic features of MUTYH-associated polyposis colorectal cancers might influence tumor behavior and patient survival, we compared survival between patients with MUTYH-associated polyposis colorectal cance...
Familial adenomatous polyposis (FAP) is a dominantly inherited colorectal tumor predisposition that results from germ-line mutations in the APC gene (chromosome 5q21). FAP shows substantial phenotypic variability: classical polyposis patients develop more than 100 colorectal adenomas, whereas those with attenuated polyposis (AAPC) have fewer than 100 adenomas. A further group of individuals, so...
introduction: due to the whole network of polyposis registers worldwide and early prophylactic treatment, survival of familial adenomatosis (fap) patients is improved. extracolonic manifestations are remarkable feature of fap. two extracolonic manifestations (duodenal adenomatosis, leading duodenal cancer and desmoid tumours) play a very important role in the reasons of death in polyposis popul...
CONTEXT Significant proportions of patients with hamartomatous polyposis or with hyperplastic/mixed polyposis remain without specific clinical and molecular diagnosis or present atypically. Assigning a syndromic diagnosis is important because it guides management, especially surveillance and prophylactic surgery. OBJECTIVE To systematically classify patients with unexplained hamartomatous or ...
introduction: chronic rhinosinusitis (crs) is a multifactorial disease. allergies are considered a predisposing factor to crs; however, this remains controversial. the objective of this research was to investigate the prevalence of co-morbidities and allergic reaction, and to specify the most common allergens in patients with confirmed crs. materials and methods: one hundred patients with sig...
Familial polyposis is of interest for its own sake as a sort of pathological curiosity and also in relation to the problem of cancer. The term " polyposis " is used to describe a widespread adenomatous proliferation of the intestinal mucous membrane, leading to the formation of multiple adenomata. It should not be applied to intestinal polyps of different histological structure, such as inflamm...
background plasmablastic lymphoma (pbl) is a relatively new entity, classified by who as a rare variant of diffuse large b cell lymphoma. the present case report introduces a 17 year old girl with chronic diarrhea, abdominal pain, intra-abdominal venous thromboses, ascites, mesenteric lymphadenopathies and small intestinal polyposis, the pathologic and immunohistochemistric examinations of the ...
OBJECTIVE To determine the pattern of cellular infiltration in nasal polyposis among Malaysian population and to compare the pattern of cellular infiltration in nasal polyposis between Malaysian and other Asian countries. MATERIAL AND METHOD This is retrospective study done on patients diagnosed with nasal polyposis from January 2008 to June 2012 in University Malaya Medical Center. Only the ...
The term 'polyposis coli' applies to a condition of multiple polyps of the large intestine and is used synonymously with 'familial polyposis' and 'multiple adenomatosis'. The latter name emphasizes the fact that the individual polyps of this disease in no way differ from adenomas observed as solitary lesions. The object of this paper is to describe the histopathology, clinical features, and fam...
There have been significant advances in our knowledge about the molecular changes that precede and accompany the development of inherited predispositions to colorectal cancer. In this review the clinical relationship to the molecular changes associated with the polyposis syndromes is presented. The aim is to put into context the diverse findings that have been shown to be associated with the de...
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