The eye presents unique opportunities and challenges when it comes to the delivery of Pharmaceuticals. While absorption by this route is bungling, there are few side effects with conventional ocular dosage forms like eye drops and eye suspensions. Several polymeric systems have been used to fabricate ocular inserts for better ocular bioavailability and retention of drug for which gelling system...

New water-soluble nontoxic nanocomposites of nanosized silver particles in a polymer matrix were synthesized by a green chemistry method. Nontoxic poly(1-vinyl-1,2,4-triazole) was used as a stabilizing precursor agent in aqueous medium. Glucose and dimethyl sulfoxide were used as the silver ion-reducing agents to yield silver nanoparticles 2-26 nm and 2-8 nm in size, respectively. The nanocompo...

Graft polymerizations of vinyl acetate onto granular corn starch were initiated by cobalt-60 irradiation of starch-monomer-water mixtures. and ungrafted poly(vinyl acetate) was separated from the graft copolymer by benzene extraction. Conversions of monomer to polymer were quantitative at a radiation dose of 1.0 IvIrad. However, over half of the polymer was present as ungrafted poly(vinyl aceta...

für Naturforschung in cooperation with the Max Planck Society for the Advancement of Science under a Creative Commons Attribution 4.0 International License. Dieses Werk wurde im Jahr 2013 vom Verlag Zeitschrift für Naturforschung in Zusammenarbeit mit der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. digitalisiert und unter folgender Lizenz veröffentlicht: Creative Commons Namen...

für Naturforschung in cooperation with the Max Planck Society for the Advancement of Science under a Creative Commons Attribution 4.0 International License. Dieses Werk wurde im Jahr 2013 vom Verlag Zeitschrift für Naturforschung in Zusammenarbeit mit der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. digitalisiert und unter folgender Lizenz veröffentlicht: Creative Commons Namen...

The presence of the crystalline regions in poly(vinyl alcohol) coating films acts as barrier clusters forcing gas molecules to diffuse a longer pathway amorphous region polymer, where diffusivity and solubility are promoted comparison. Evaluating influence on oxygen property semi-crystalline polymer is thus essential prepare better films. Poly(vinyl with varying induced crystallinity were prepa...

In recent years natural polymers have been widely used in biomedical applications. Application of natural and biocompatible polymers in wound dressing, medical sutures and tissue engineering are extensively growing. Additional properties are provided when metal nanoparticles such as silver and gold are incorporated in to the fibers. However, nowadays nanofibers due to their inherent properties ...

Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors. Basic fibroblast growth factor and vascular endothelial growth factor are heparin-binding growth factors that synergistically enhance angiogenesis. Mild, in situ encapsulation of both basic fibroblast growth factor and vascular endothelial grow...

Poly(vinyl alcohol) (a), its partially hydrolyzed product or poly(vinyl alcohol-co-vinyl acetate) (b) and poly(ethylene-co-vinyl alcohol) (c) are all industrially significant polymers used mainly for fiber and film, size and emulsifier/stabilizer, and gas-barrier material, respectively. In this thesis, these vinyl alcohol-based polymers have been discussed from two aspects: the molecular struct...