In Shandong Province, China, programmes were initiated in 1991 for mass immunization against poliomyelitis and for the immediate reporting of acute flaccid paralysis (AFP). The incidence of non-poliomyelitis AFP was found to be 0.46-0.61 cases per 100 000 children per annum. It appeared that illness resembling the Guillain-Barre syndrome was underreported. The incidence of such illness peaked a...

A striking feature of paralytic poliomyelitis has been its ever changing epidemiology. In the past, changes seem to have come about in the course of natural evolution from an endemic to an epidemic pattern, first in one part of the world, and then in another. At present, the use of effective vaccines for prevention and for greatly reducing circulation of wild strains of the virus, have apparent...

Poliomyelitis associated with live strain vaccine is defined as the paralytic form of the acute anterior poliomyelitis related to the vaccine strain. Since these strains behave similarly to the wild-type virus, we can differentiate, epidemiologically, two types of vaccine-associated poliomyelitis: cases in which the patient was vaccinated and cases in which the patient had had contact with vacc...

THIS is the sixth report of the Virus Reference Laboratory and, as in previous reports, only the more interesting and rewarding aspects of the work will be presented. POLIOMYELITIS. Laboratory Diagnosis. During 1962 there were thirty-one cases of paralytic poliomyelitis in Northern Ireland, including one death, giving an attack rate of 2.2 per 100,000 of the population. Type 1 poliovirus was is...

INTRODUCTION Poliomyelitis causes selective destruction of anterior horn cells and usually has a stable disease course post-infection. We assessed the excitability characteristics in patients with a stable course after past poliomyelitis and compared them with changes described in amyotrophic lateral sclerosis (ALS). METHODS The excitability characteristics of motor and sensory nerves were st...

OBJECTIVE To study the trends of paralytic poliomyelitis in pre Pulse Polio Immunization period. SETTING Hospital based sentinel surveillance. METHODS Analysis of 6704 line-listed poliomyelitis cases from January 1989 to December 1994 attending the Department of Physical Medicine and Rehabilitation. RESULTS 85% of all cases reported in Delhi were from this center. A decline in alternate y...

We collected 30 cases of vaccine associated paralytic poliomyelitis (VAPP) from 4081 cases of acute flaccid palsies cases notified from 1989 to 1995 to the Brazilian Ministry of Health. There were 30 VAPP cases with 56% of children younger than 1 year old, 56.7% of female. 46% of cases were reported in the Northeast. Ten P2 vaccine virus, 8 P3 and 2 P1 and associations amongst them were isolate...