Post-polio syndrome is a condition characterized by increased muscle weakness, atrophy, fatigue and pain developing several years after the acute polio event. We describe a 52-year-old patient who experienced post-polio syndrome; he had contracted acute paralytic poliomyelitis at 12 months of age, shortly after the third dose of Salk polio vaccine.

Some of their observations are correct, but some observations need clarification, while some issues have been left out in the editorial. Their observations suggest inadequate vaccine coverage and non-vaccination are reasons for increase in number of polio cases in the year 2002. The authors had also indicated that OPV vaccine has not made much impact. In case OPV vaccine had made any major impa...

a serum survey was conducted to determine the immune status of children 2 months to 6 years old to polio virus type i, ii and iii related to the history of oral polio vaccination in fashapouye (a rural area in the south of teheran). 566 serum samples were obtained from children in 9 different villages and microneutra lization test was performed on 1;10 dilution of these sera. the study revealed...

The World Health Organization declared India among other 10 countries in South East Region - as 'polio-free' in 2014. Since then, the Government of India (GoI) has scaled up its initiatives against polio endgame which targets virus eradication and sequential withdrawal of type 2 virus from oral polio vaccine (OPV). However, prior to choosing the switch from trivalent OPV (t-OPV) to bivalent OPV...

Background.  Live vaccines may have nonspecific beneficial effects on morbidity and mortality. This study examines whether children who had the live-attenuated oral polio vaccine (OPV) as the most recent vaccine had a different rate of admissions for infectious diseases than children with inactivated diphtheria-tetanus-pertussis-polio-Haemophilus influenzae type b vaccine (DTaP-IPV-Hib) or live...

The world is now in the 24 year of the Global Polio Eradication Initiative. Halfway through that initiative in 2000, the island of Hispaniola saw an outbreak of vaccine derived poliovirus [1]. The implications of this outbreak and multiple subsequent isolations of Sabin strains that are estimated to have circulated in communities for a year or more are now causing a reconsideration of the optim...

Prolonged excretion of poliovirus can occur in immunodeficient patients who receive oral polio vaccine, which may lead to propagation of highly divergent vaccine-derived polioviruses (VDPVs), posing a concern for global polio eradication. This study aimed to estimate the proportion of primary immunodeficient children with enterovirus infection and to identify the long-term polio/nonpolio entero...

Polio eradication is on the cusp of success, with only a few regions still maintaining transmission. Improving our understanding of why some regions have been successful and others have not will help with both global eradication of polio and development of more effective vaccination strategies for other pathogens. To examine the past 25 years of eradication efforts, we constructed a transmissio...

objective: as we are approaching the global eradication of wild poliovirus, laboratory surveillance of poliovirus by the gold standard cell culture method becomes increasingly important. as there is a lot of concern about accurate and sensitive detection of imported wild and vaccine derived polioviruses (vdpvs) in polio-free countries, in this study we assessed and compared the sensitivity of t...