Purpose Current perimeters use fixed grid patterns. We test whether a grid based on an individual's retinal nerve fiber layer (RNFL) thickness profile would find more visual field (VF) defects. Methods We describe the defect-based method for choosing test locations. First, the 26 VF locations with the highest positive predictive value to detect glaucoma from the 24-2 pattern are chosen. An ad...

Localization of mRNA is a well-described mechanism to account for the asymmetric distribution of proteins in polarized somatic cells and embryos of animals. In zygotes of the brown alga Fucus, F-actin is localized at the site of polar growth and accumulates at the cell plates of the first two divisions of the embryo. We used a nonradioactive, whole-mount in situ hybridization protocol to show t...

Localization of mRNA is a well-described mechanism to account for the asymmetric distribution of proteins in polarized somatic cells and embryos of animals. In zygotes of the brown alga FUCUS, F-actin is localized at the site of polar growth and accumulates at the cell plates of the first two divisions of the embryo. We used a nonradioactive, whole-mount in situ hybridization protocol to show t...

Background CMR tagging in polar patterns is desirable because of its close compatibility to the annular geometry and motion of the left ventricle in short axis view. This circular symmetry does not exist in some pathological cases neither in the normal long axis view. An oval-shaped pattern is more suitable for assessment of the deformation in these conditions. Herein, we present the non-unifor...

Cells of the cellular slime mould D. discoideum were allowed to form into spherical aggregates, by shaking vegetative cells as a suspension in phosphate buffer. In such conditions, grex polarity is never established and surface sheath is not formed (Loomis, 1975 a). Despite the absence of such characteristics of normal development, differentiation of prespore cells, as tested for by immunofluor...

Spatio-temporal phenomena used to be represented in Cartesian Coordinate Systems, and time is perceived linear. This way of representing time may not be appropriate for representing and analysing some types of natural and human phenomena, which occur in time cycles. This paper thus proposes the use of polar coordinate systems. Polar angles are used to represent time, which can be clock time at ...

The 3-D structure of the solar wind is strongly dependent upon the Sun’s activity cycle. At low solar activity a bimodal structure is dominant, with a fast and uniform flow at the high latitudes, and slow and variable flows at low latitudes. Around solar maximum, in sharp contrast, variable flows are observed at all latitudes. This last kind of pattern, however, is a relatively short-lived feat...