In the last five years, everolimus has demonstrated efficacy in the treatment of neuroendocrine tumors (NETs) of different origins; its efficacy and safety were explored in the RADIANT trials, the last of which (RADIANT-4) has been recently published (December 2015). Overall, evidence collected from the RADIANT studies holds promise to change clinical practice for the treatment of NETs.In this ...

The energy performance of radiant slab cooling relative to conventional air systems to be clarified for climates from cold and dry to very hot and humid. EnergyPlus simulations were used to compare the energy performance of 1) radiant slab cooling combined with a dedicated outdoor air system and 2) a variable air volume system. Simulation results show that the radiant slab system provided 10% t...

Twenty-six bicycle helmets and their associated visors were characterized for radiant heat transfer using a thermal manikin headform in a climate chamber to assess their ability to protect the wearer from heating by the sun. A single configuration for applied radiant flow of 9.3 W was used to assess the roles of the forward and upper vents and the visor. The helmets shielded 50-75% of the radia...

• A novel radiant-convective cooling system is proposed. The thermal comfort, energy and economic performance are experimentally studied. proposed has better indoor comfort than split air-conditioners. higher efficiency ratio Split air-conditioners have limitations in terms of local comfortability. Radiant systems (RCSs) cannot be used most residential buildings, due to its lack space for a cen...

The body temperatures of infants weighing less than 1500 g under radiant warmers during routine care were documented in the first week of life. Ten infants (median gestational age 28 weeks, median birthweight 913 g) were studied. During 30 nursing interventions (mean 9.2 minutes) mean oesophageal and foot temperature changed 0 degrees C and -0.11 degrees C, respectively. A radiant warmer may li...

This thesis develops a novel resource sharing approach for solving inverse radiant enclosure problems based on distributed construction which is then extended to provide a new controls algorithm for complex energy systems. Specifically, the problem of determining the temperature distribution needed on the heater surfaces to achieve a desired design surface temperature profile is recast as a dis...

The goal of the inverse analysis is to find a set of heaters over some parts of boundary, called the heater surface, to satisfy the desired heat flux profile over the design surface. Micro-genetic algorithm is employed to inverse design of a radiant enclosure with absorbing-emitting medium. The direct problem of radiative heat transfer is solved by the discrete transfer method. The inverse prob...

This study describes and evaluates a simple method of neuroprotective hypothermia for infants with hypoxic-ischaemic encephalopathy (HIE). Five term infants with HIE were cooled by applying soft, cold gel bags to the head. A radiant warmer, set to 34 degrees C, servo-controlled the temperature measured at a probe between the infant's back and the mattress. The infants' heads were shielded from ...