Food adulteration and mislabeling may pose potential health risks and trust issues to consumers, particularly for high-valued wine products. The current analytical methods and anticounterfeit labeling techniques are insufficient to determine the identity and point of origins for these products. This application note describes a metabolomic profiling method to trace the origins of wine products ...

Cellular responses to external stimuli depend on dynamic features of multipathway network signaling; thus, cell behavior is influenced in a complex manner by the environment and by intrinsic properties. Methods of multivariate systems analysis have provided an understanding of these convoluted effects, but only for relatively simplified examples in vitro. To determine whether such approaches co...

In recent years, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has become the standard for routine bacterial species identification due to its rapidity and low costs for consumables compared to those of traditional DNA-based methods. However, it has been observed that strains of some bacterial species, such as Acinetobacter baumannii strains, cannot...

Sensitive and predictive DILI (Drug Induced Liver Injury) biomarkers are needed in drug R&D to improve early detection of hepatotoxicity. The discovery of DILI biomarkers that demonstrate the predictive power to identify individuals at risk to DILI would represent a major advance in the development of personalized healthcare approaches. In this healthy volunteer acetaminophen study (4g/day for ...

This paper focuses on a rapid and nondestructive way to discriminate the geographical origin of Anxi-Tieguanyin tea by near-infrared (NIR) spectroscopy and chemometrics. 450 representative samples were collected from Anxi County, the original producing area of Tieguanyin tea, and another 120 Tieguanyin samples with similar appearance were collected from unprotected producing areas in China. All...

Adulteration of edible vegetable oils is a very serious problem affecting its commercial value and customers’ health. FT-NIR and Confocal Micro-Raman have been explored for discriminating adulteration of sesame oils. The soybean, corn, and peanut oil were mixed into sesame oils in the range of 5~20%(v/v),respectively,and their Confocal Micro-Raman and FT-NIR spectra were collected. Principal co...

This paper reports the application of near infrared (NIR) spectroscopy and pattern recognition methods to rapid and automatic discrimination of the genotypes (parent, transgenic, and parent-transgenic hybrid) of cotton plants. Diffuse reflectance NIR spectra of representative cotton seeds (n = 120) and leaves (n = 123) were measured in the range of 4000-12000 cm(-1). A practical problem when de...

Potential of front-face fluorescence spectroscopy was evaluated to classify muscles according to their chemical and rheological characteristics. Seven bovine muscles (Semitendinosus, Semimembranosus, Tensor fasciae latae, Rectus abdominis, Longissimus thoracis et lumborum, Triceps branchii and Infraspinatus) were taken from 14 animals of the Charolais breed. Chemical characteristics and rheolog...

For an electronic nose (E-nose) in wound infection distinguishing, traditional learning methods have always needed large quantities of labeled wound infection samples, which are both limited and expensive; thus, we introduce self-taught learning combined with sparse autoencoder and radial basis function (RBF) into the field. Self-taught learning is a kind of transfer learning that can transfer ...

Human saliva is a unique biofluid which can reflect the physiopathological state of an individual. The wide spectrum molecules present in saliva, compounded by close association salivary composition to serum metabolites, provide valuable information for clinical diagnostic applications through highly sensitive vibrational spectroscopic techniques such as Raman spectroscopy. However, nature term...