INTRODUCTION Leukocyte-platelet rich fibrin belongs to a second generation of platelet concentrates that does not need biochemical blood manipulation. It is used for tissue healing and regeneration in periodontal and oral-maxillofacial surgery. We report two cases of hyperplastic gingival lesions treated by exeresis and application of leukocyte-platelet rich fibrin membranes in order to improve...

Platelet-rich fibrin (PRF) belongs to a new generation of platelet concentrates geared to simplified preparation without biochemical blood handling. In this initial article, we describe the conceptual and technical evolution from fibrin glues to platelet concentrates. This retrospective analysis is necessary for the understanding of fibrin technologies and the evaluation of the biochemical prop...

Objectives: To evaluate platelet-rich fibrin (PRF) in horses and compare temporal release of growth factors (GF) to platelet-rich

Fibrin, the coagulation end product, consolidates the platelet plug at sites of vascular injury and supports the recruitment of circulating platelets. In addition to integrin αIIbβ3, another as-yet-unidentified receptor is thought to mediate platelet interaction with fibrin. Platelet glycoprotein VI (GPVI) interacts with collagen and several other adhesive macromolecules. We evaluated the hypot...

Abstract The aim of this article is to present the clinical application leukocyte-platelet-rich fibrin (L-PRF) at immediately extracted site after implant placement. A 37-year-old male patient reported Department Prosthodontics, Bhojia Dental college Budh Baddi Dist Solan Himachal Pradesh 173205 with chief complaint decayed teeth in posterior region and wants a fixed prosthesis. On day surgery,...

Treatment of intrabony defects is always a difficult task to manage for periodontist. Various problems have been encountered like black triangle, increased food lodgement, plaque accumulation and ultimately failure procedure were experienced. Thus more conservative approaches papilla preservation flaps Non-incised Papillae surgical are preferred. But due drawbacks existent techniques there was ...

Introduction: Gold standard for alveolar cleft bone grafting is autogenous bone. Advantage of adding the growth factors to the bone is established, so adding PRF to the autogenous bone may have beneficial effects. Methods:  Platelet-rich plasma admixed with autogenous bone and as a biologic membrane over the bone grafted alveolar cleft was used. Results:  Autogenous bone in all (four cases...

Platelet concentrates for topical and infiltrative use - commonly termed Platetet-Rich Plasma (PRP) or Platelet-Rich Fibrin (PRF) - are used or tested as surgical adjuvants or regenerative medicine preparations in most medical fields, particularly in sports medicine and orthopaedic surgery. Even if these products offer interesting therapeutic perspectives, their clinical relevance is largely de...