نتایج جستجو برای: plasmatocyte

تعداد نتایج: 42  

2011
Oana Marcu Matthew P. Lera Max E. Sanchez Edina Levic Laura A. Higgins Alena Shmygelska Thomas F. Fahlen Helen Nichol Sharmila Bhattacharya

Alterations and impairment of immune responses in humans present a health risk for space exploration missions. The molecular mechanisms underpinning innate immune defense can be confounded by the complexity of the acquired immune system of humans. Drosophila (fruit fly) innate immunity is simpler, and shares many similarities with human innate immunity at the level of molecular and genetic path...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Yasunori Oda Hitoshi Matsumoto Maiko Kurakake Masanori Ochiai Atsushi Ohnishi Yoichi Hayakawa

Growth-blocking peptide (GBP) is an insect cytokine that stimulates a class of immune cells called plasmatocytes to adhere to one another and to foreign surfaces. Although extensive structure-activity studies have been performed on the GBP and its mutants in Lepidoptera Pseudaletia separata, the signaling pathway of GBP-dependent activation of plasmatocytes remains unknown. We identified an ada...

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