Introduction: During its life cycle, malaria parasite has to traverse successfully through widely diverse environmental milieu of mosquito mid gut, RBC cytosol and human circulatory system where it is exposed to dramatic changes of extracellular milieu in terms of pH, osmolarity and ionic constituents. Therefore, the aim of this study was to examine the possible changes in the cations (Na+, K+,...

Information from animal studies has demonstrated the harmful effects of zinc supplementation on copper transport. Although some studies have been carried out in humans, the effect on humans has not been as well documented as the effect on animals. Forty-seven healthy volunteers (26 women and 21 men) took part in a double-blind cross-over trial which lasted for 12 weeks. The subjects were asked ...

A series of studies were conducted to determine the effect of supplemental trace mineral source on growth performance, morbidity, and trace mineral status in growing beef cattle. The first experiment evaluated supplemental trace minerals from sulfate, organic, or hydroxy sources on growth performance and morbidity. Crossbreed beef calves were assigned to 1 of 3 treatments consisting of suppleme...

Rhesus monkeys were fed a diet marginally deficient in zinc (4 ppm zinc) throughout pregnancy and were monitored for changes in hematological, biochemical, and immunological parameters. This dietary zinc level was chosen because it did not produce an overt deficiency syndrome when fed for 10 wk to nonpregnant monkeys. Deprived animals were compared to control groups fed a zinc replete (100 ppm)...

It has been suggested that one risk factor in the development of hypertension and vascular disease may be abnormal copper and zinc metabolism. In the current study we tested the hypothesis that hypertension itself may result in alterations in the metabolism of these essential elements. Dahl salt-sensitive rats were fed diets containing 0.4 or 8.0% NaCl for 32 days. At the conclusion of the stud...

Copper and zinc are essential trace elements which play an important role in various biological processes. Along with various cytokines, glucocorticoids, glucagon and insulin, the acute-phase protein metallothionein is involved in the regulation of immune cell functions. Metallothionein is the central protein regulating zinc concentration. Zinc deficiency is often found in patients with chronic...

background: leukoplakia is a common, potentially premalignant lesion with malignant transformation rate from 1 to 17% with highest transformation rate for the lesions on the floor of the mouth, soft palate and tongue. one of the main etiological factors is consuming areca nut and its commercial preparations which generate high levels of reactive oxygen species during their metabolism. so the ai...

206 2. Day C, McCollum EV. Effect of acute dietary zinc deficiency in rat. Proc Exp Biol Med 1940;45:282-7. 3. Saxena N, Sharma RP, Singh VS. A study of serum zinc and copper levels in psoriasis. Indian J Dermatol Venereol Leprol 1990;56:216-8. 4. McMillan C, Rowe D. Plasma zinc in psoriasis: Relationship to surface area involvement. Br J Dermatol 1983;108:301-5. 5. Portnoy K, Molokhia M. Zinc ...

BACKGROUND Several micronutrients are essential for adequate growth of children. However, little information is available on multiple micronutrient status of school children in Ethiopia. The present study was designed to evaluate the relationship between multiple micronutrient levels and nutritional status among school children. METHOD In this cross-sectional study, anthropometric data, blood...