Plant-based platforms have been successfully applied for the last two decades for the efficient production of pharmaceutical proteins. The number of commercialized products biomanufactured in plants is, however, rather discouraging. Cytokines are small glycosylated polypeptides used in the treatment of cancer, immune disorders and various other related diseases. Because the clinical use of cyto...

Probiotics can improve growth, survival and resistance to pathogenic organisms of the cultivated species in aquaculture systems with water recirculation. However, their possible benefits on biofloc systems have been less studied. In this study, the benefits of Bacillus amyloliquefaciens bacterium, on a biofloc culture of Litopenaeus vannamei were evaluated. B. amyloliquefaciens was applied as d...

Plant and human pathogens have evolved disease factors to successfully exploit their respective hosts. Phytopathogens utilize specific determinants that help to breach reinforced cell walls and manipulate plant physiology to facilitate the disease process, while human pathogens use determinants for exploiting mammalian physiology and overcoming highly developed adaptive immune responses. Emergi...

Approximately all sequenced archaeal and half of eubacterial genomes have some sort of adaptive immune system, which enables them to target and cleave invading foreign genetic elements by an RNAi-like pathway. CRISPR–Cas (clustered regularly interspaced short palindromic repeats–CRISPR-associated proteins) systems consist of the CRISPR loci with multiple copies of a short repeat sequence separa...

In the last two decades, advances in network science have facilitated discovery of important systems’ entities diverse biological networks. This graph-based technique has revealed numerous emergent properties a system that enable us to understand several complex processes including plant immune systems. With accumulation multiomics data sets, comprehensive understanding plant–pathogen interacti...

To study the effect of depression on the endocrine and immune systems, 557 male freshman and sophomore medical students (20-30 years old) were given Beck's Depression Inventory. Students with marks 5 or above were selected as the control (n=26) and those with marks of 20 or higher were chosen as the test group (n=27). All of the students were subjected to the following tests: CBC, different...

Artificial Immune Systems (AIS) have long been used in the field of computer security and especially in Intrusion Detection systems. Intrusion detection based on AISs falls into two main categories. The first generation of AIS is inspired from adaptive immune reactions but, the second one which is called danger theory focuses on both adaptive and innate reactions to build a more biologically-re...

In nature, plants constantly have to face pathogen attacks. However, plant disease rarely occurs due to efficient immune systems possessed by the host plants. Pathogens are perceived by two different recognition systems that initiate the so-called pattern-triggered immunity (PTI) and effector-triggered immunity (ETI), both of which are accompanied by a set of induced defenses that usually repel...