Implantation and placentation are critical steps for successful pregnancy. The pig has a non-invasive placenta and the uterine luminal epithelium is intact throughout pregnancy. To better understand the regulation mechanisms in functions of endometrium at three certain gestational stages that are critical for embryo/fetal loss in pigs, we characterized microRNA (miRNA) expression profiles in th...

Poor placentation, which manifests as pre-eclampsia and fetal growth restriction, is a major pregnancy complication. The underlying cause is a deficiency in normal trophoblast invasion of the spiral arteries, associated with placental inflammation, oxidative stress, and an antiangiogenic state. Peripartum therapies, such as prenatal maternal corticosteroids and magnesium sulphate, can prevent s...

BACKGROUND The physiopathology of Preeclampsia (PE) is characterized by a deficiency in the process of placentation, systemic endothelial dysfunction and Central Nervous System (CNS) hyperflow. From a clinical point of view, it would be interesting to determine the occurrence of these phenomena before the onset of clinical manifestations of the disease, raising the possibility of new methods fo...

2-year study involving macroscopic examination of twin placentae was conducted at the Korle Bu Teaching Hospital in Accra, Ghana to determine the proportions of the various types of twin placentation, cord insertions and number of cord vessels and their relationships. had monochori-onic diamniotic placentae; only one (0.1%, 95% CI 0.0%–0.8%) had monochorionic monoamniotic pla-centation. Of 1529...

because of an unknown factor, the frequency of complicated pregnancy with placenta previa has been raised during past decade. this study was designed to deepen our understanding of risk factors and outcomes of placenta previa in our country. this study investigated 694 cases of placenta previa comparing with 600 healthy pregnant women with not overlie placenta in two referral and tertiary obste...

Placental and fetal tissues were recovered from the uteri of 59 pregnant elephant that ranged in estimated age from day 1 B to month 21 of gestation. Incubation of placenta and fetal gonad, alone or in combination, with tritium-labelled cholesterol, pregnenolone and androstenedione failed to yield any labelled progestagens or oestrogens from placenta, but did produce small amounts of labelled p...

Implantation, trophoblast development and placentation are crucial processes in the establishment and development of normal pregnancy. Abnormalities of these processes can lead to pregnancy complications known as the great obstetrical syndromes: preeclampsia, intrauterine growth restriction, fetal demise, premature prelabor rupture of membranes, preterm labor, and recurrent pregnancy loss. Ther...

The success of pregnancy depends on a receptive endometrium, a normal blastocyst, a synchronized cross-talk at the maternal–fetal interface at the time of implantation, and finally a successful placentation and remodeling of uterine vasculature. In routine, less than 5% of oocytes collected in in vitro fertilization (IVF) cycles and only 20 to 25% of embryos transferred lead to a birth. Implant...