727 Abstract: The gelatin cap-sule shell may be soft or hard depending on their formulation. Capsules are intended to be swallowed whole by the patient. In instances where patients (especially children) are unable to swallow capsules, the contents of the capsule can be removed and added (e.g., sprinkled) on soft food immediately before ingestion. In the manufacture of pharmaceuticals, encapsula...

background: regarding to the growing prevalence of nonalcoholic fatty liver disease (nafld), concentrating on various strategies to its prevention and management seems necessary. the aim of this study was to determine the effects of symbiotic on c‑reactive protein (crp), liver enzymes, and ultrasound findings in patients with nafld. methods: eighty nafld patients were enrolled in this randomize...

objective: type 2 diabetes mellitus is a complex metabolic disorder with adverse cardiovascular risk. chromium (cr) is an essential nutrient and its role in carbohydrate and lipid metabolism has not been clarified especially in iran. the aim of this study was to evaluate the effect of chromium picolinate administration on blood glucose, hba1c, lipid profile and lipid peroxidation in type 2 diab...

BACKGROUND Caffeine is known to inhibit phosphodiesterases, to mobilise intracellular calcium, and to act as an antagonist at adenosine receptors, all of which can potentially alter nitric oxide (NO) production. It was therefore hypothesised that caffeine may alter exhaled NO (eNO) levels. METHODS In a randomised, single blind, crossover manner, 12 normal subjects consumed either (1) coffee a...

Background: Migraine is a common neurobiological disorder and various methods have been proposed for its treatment, including herbal remedies. Sodae is an herbal capsule produced and marketed by “Booali Daroo” Pharmaceutical Company, based on Iran's traditional medicine, in compliance with the instructions of the Food and Drug Administration of Iran and with a license issued by this administrat...

In terms of advancement of life to meet the challenges new method for neuropsychopharmacological research are continually developing to ensure superior safety, accuracy, efficacy, precision etc. In this experiment, we suggested and validated two neuropsychopharmacological testing methods, these are Numeral Finding (NF) and Typo Revealing (TR) tests for the determination of attention in healthy ...

This study was intended to evaluate the efficacy and safety of Tongxinluo capsule for hypertension. Search Strategy. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, The PubMed, EMBASE, Chinese Bio-Medical Literature Database (CBM), Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database, and Wan-fang Data started fr...

In the present study, a capsule formulation composed of enteric coated granules of Lactobacillus acidophilus ATCC 4962 was developed using Eudragit L30D-55 as enteric polymer. Optimization of the capsule formulation was achieved with a maximum viable cell count after 2 h of incubation in acid medium and disintegration time of 1 h in buffer pH 6.8. The amount of Eudragit L30D-55 in the capsules ...

Objective: Type 2 diabetes mellitus is a complex metabolic disorder with adverse cardiovascular risk. Chromium (Cr) is an essential nutrient and its role in carbohydrate and lipid metabolism has not been clarified especially in Iran. The aim of this study was to evaluate the effect of chromium picolinate administration on blood glucose, HbA1c, lipid profile and lipid peroxidation in type 2 diab...