Reconstructive hand surgeries restore key pinch to individuals with pinch force deficits caused by tetraplegia. Data that define the magnitudes of force necessary to complete functional key pinch tasks are limited. This study aims to establish target pinch forces for completing selected tasks that represent a range of useful functional activities. A robot arm instrumented with a force sensor co...

PURPOSE Surgical transfers of muscles are used to restore lateral pinch in tetraplegia; however, outcomes are variable. The purpose of this study was to compare activation of the brachioradialis (Br) after transfer to the flexor pollicis longus during maximum effort in its primary function (elbow flexion) with maximum effort in its postoperative function (lateral pinch) and to record Br activat...

Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase (ILK)-PINCH-Parvin-α) complex. PINCH itself binds to ILK and to another protein known as Rsu-1 (Ras suppressor 1). We generated PINCH 1 and PINCH 2 Double knockout mice (referred as PINCH DKO mice). PINCH2 elimination was systemic whereas PINCH1 el...

Supply chain managers are trying to maximize the profitable operation of their manufacturing and distribution supply chain, but due to global competition in process industries and complexities of the supply chain processes together with large computational times, it has made optimization of supply chain management (SCM) quite difficult. Recently, Knowledge management (KM) is a new important inf...

Integrated Process Design aims at a holistic approach to process design, retrofitting, and operations planning. Cost and energy ‘‘targets’’ (i.e. the minimum possible values for these objectives) can be calculated based on pinch technology, which defines the enthalpy at which the hot and cold process streams are separated by the minimum temperature difference in heat exchanger networks. This ap...

BACKGROUND Measuring and comparing grip and pinch strengths with their normative data is a valid method to detect intensity of the numerous damages of hand. This research was carried out with the aim of establishing normative data of grip strength and three types of pinch strengths (Tip, Key and Palmar) in healthy Iranian adults. METHODS In this cross-sectional study, the study population was...

Introduction: Grip and pinch strength assess the function of hand and is considered as a sign of general health. Considering the high prevalence of related-work musculoskeletal disorders (WMSDs) due to the incongruity of work with the workers and preventability of diseases that are caused by such incongruity, we decided to study the relationship between maximum oxygen consumption (Vo2max) and w...

OBJECTIVE Particularly interesting new cysteine-histidine rich protein (PINCH) is an important component of the local adhesion complexes and upregulated in several types of malignancies, and involved in the incidence and development of tumours. PINCH expression is also independently correlated with poorer survival in patients with colorectal cancer. However, there is no study of PINCH in gastri...