Aging, an inevitable and extremely complex, multifactorial process, is characterised by the progressive degeneration of organ systems and tissues. It is largely determined by genetics, and influenced by a wide range of environmental factors, such as diet, exercise, exposure to microorganisms, pollutants, and ionising radiation. This explains why two people of the same age may differ markedly in...

BACKGROUND AND OBJECTIVE Herein an overview is provided of the causes, consequences, and significance of photodynamic therapy (PDT)-mediated effects on tumor oxygenation and blood flow during illumination. STUDY DESIGN/MATERIALS AND METHODS Techniques particularly valuable to this research have included tissue oxygen tension measurement by the Eppendorf pO2 Histograph; spatial quantification ...

Advances in medical care have led to increasing numbers of complex, high-risk obstetric patients. Specialist training and a sound knowledge of normal maternal physiology are essential to optimize outcomes. One of the earliest observed changes is peripheral vasodilatation; this causes a fall in systemic vascular resistance and triggers physiological changes in the cardiovascular and renal system...

Maintenance of proper serum phosphate concentrations is required for healthy life, and critical for normal skeletal development and integrity. Several hormones and regulatory factors such as vitamin D, parathyroid hormone (PTH), and the phosphatonins (FGF-23, sFRP-4, MEPE) among others, may play a role only in the long-term regulation of phosphorus homeostasis.FGF23 is part of a previously unre...