behçet’s disease (bd) is a multisystem disorder with potential ability to influence the pregnancy outcome and pregnancy is associated with several physiologic alterations which can lead to potential changes in the course of the disease. we studied 77 pregnancies in 69 women with bd. the disease activity was calculated by two methods for three periods of before, during and after pregnancy to eva...

background: autologous skin graft is frequently used in the field of plastic, and reconstructive surgery. the engraftment is dependent upon revascularization and angiogenesis, which can be regulated by different factors. in addition to its hematopoietic effects, erythropoietin is shown to positively affect the wound healing process. objectives: we studied effects of human erythropoietin on reva...

Although cannabis may have potential therapeutic value, inhalation of a combustion product is an undesirable delivery system. The aim of the study was to investigate vaporization using the Volcano((R)) device as an alternative means of delivery of inhaled Cannabis sativa. Eighteen healthy inpatient subjects enrolled to compare the delivery of cannabinoids by vaporization to marijuana smoked in ...

We have previously reported our studies of blood cardioplegia and our delivery system for it (1, 2). Our experimental results showing blood cardioplegia to be superior to asanguineous cardioplegia were reported recently (3, 4), and we have used blood cardioplegia for the past two and a half years. Although our clinical results have been gratifying, and the whole blood cardioplegia system was de...

INTRODUCTION — Conventional mechanical ventilation refers to the delivery of full or partial ventilatory support by a volume-cycled mechanical ventilator or by pressure support. It also can include the maintenance of positive airway pressure at the end of exhalation, ie, positive end-expiratory pressure (PEEP) [1]. (See "Physiologic and pathophysiologic consequences of positive pressure ventila...

There have been few case reports of isolated elevation of alkaline phosphatase beyond the normal physiologic amount with subsequent return to baseline after delivery. Here we present a similar case of extreme elevation of alkaline phosphatase in a pregnancy complicated by gestational diabetes and subsequently by neonatal alloimmune thrombocytopenia (NAIT).

Trauma affects up to 6% to 7% of all pregnancies, and accounts for up to 46% of maternal death. Adverse consequences such as preterm labor and delivery, abruptio, fetomaternal hemorrhage, and fetal demise may be seen with even apparently minor degrees of injury. Maternal physiologic considerations are reviewed and a protocol for evaluation and management of the injured gravida is presented.

extract: sever coughs of the little zahra who has 8 months old informed you even before that her parents inter to the ward. zahra's developmental needs in terms of emotional, physical and social will required a detailed cares in her hospitalization period. but at this time her breathing problem may attracted your attention. needs and differences of the mentioned infant explain below. zahra...

Polyethylenimines (PEIs) are the most efficient synthetic vectors for gene delivery available to date. With its high charge density and strong proton-buffering effect, PEI has an ability to condense DNA and small interfering RNA at physiologic pH. However, the polymer suffers from the disadvantage of high cellular toxicity. To reduce its cellular toxicity, we synthesized linear PEIs by partial ...

Introduction A particularly desirable feature of controlled drug delivery is self-regulation, wherein physiological feedback actively regulates release kinetics. Extant systems in this domain commonly employ stimuli-responsive vehicles that rely on internal triggers to precipitate release, such as temperature, pH, or chemical reactions. 2 The sensitivity of these triggers can be tuned by biomat...