Various imaging modalities are available to study the heart, including ultrasound, single photon emission computed tomography, positron emission tomography, computed tomography, and magnetic resonance imaging [1–4]. These modalities are fundamentally different and, consequently, different information is deduced from the images they generate. This paper describes briefly the physical principles ...

INTRODUCTION Extraosseous uptake of 99mTc-hydroxymethylene diphosphonate is a common situation of variable clinical relevance. CASE PRESENTATION A 52-year-old Caucasian woman presented to our department for breast cancer staging. A 99mTc-hydroxymethylene diphosphonate bone scan was performed and showed focal pelvic hyperfixation that disclosed intrauterine device migration into the anterior w...

skeletal involvement is the second most common site of metastases after lymph nodal metastases in patients with prostate cancer. the skeletal metastases from prostate cancer are osteoblastic in nature and show increased tracer avidity on the bone scan. focal tracer avid lesion in skeleton especially in skull requires the careful examination by further investigation. the patients with skull meta...

Osteoma is a benign bone-forming tumor that usually arises in the craniofacial bones and rarely in the long bones. Clavicular involvement is extremely rare. We report a 51-year-old woman with osteoma of the left clavicle. Radiograph of the left shoulder showed a well-defined lobulated blastic mass in the proximal and mid-portion of the left clavicle. Bone scintigraphy was performed 4 hours afte...

Skeletal involvement is the second most common site of metastases after lymph nodal metastases in patients with prostate cancer. The skeletal metastases from prostate cancer are osteoblastic in nature and show increased tracer avidity on the bone scan. Focal tracer avid lesion in skeleton especially in skull requires the careful examination by further investigation. The patients with skull meta...

Single photon emission computed tomography (SPECT) is the state-of-the-art imaging modality in nuclear medicine despite the fact that only a few new SPECT tracers have become available in the past 20 years. Critical for the future success of SPECT is the design of new and specific tracers for the detection, localization, and staging of a disease and for monitoring therapy. The utility of SPECT ...

The Geant4 Application for Emission Tomography (GATE) is an advanced open-source software dedicated to Monte-Carlo (MC) simulations in medical imaging involving photon transportation (Positron emission tomography, single photon emission computed tomography, computed tomography) and in particle therapy. In this work, we extend the GATE to support simulations of optical imaging, such as biolumine...

Over the past decade, quantitation of cardiac single-photon emission computed tomography (SPECT) data, once limited to perfusion assessment, has been extended to global and regional function assessment for both the left and the right ventricle, as well as to measurement of additional cardiac parameters of diagnostic and prognostic interest. A number of commercially available quantitative algori...

BACKGROUND Generally, attenuation correction is made by incorporating a linear attenuation coefficient, which is based on the attenuation coefficient map (mu-map) created from a computed tomography scan, into the ordered subsets-expectation maximization reconstruction method in non-uniform domains. A non-uniform Chang's attenuation correction method that uses the mu-map created from a computed ...