Characterisation of the photolytic HONO-source in the atmosphere simulation chamber SAPHIR F. Rohrer, B. Bohn, T. Brauers, D. Brüning, F.-J. Johnen, A. Wahner, and J. Kleffmann Institut für Chemie und Dynamik der Geosphäre II: Troposphäre, Forschungszentrum Jülich, Jülich, Germany Physikalische Chemie/FB C, Bergische Universität Wuppertal, Wuppertal, Germany Received: 11 August 2004 – Accepted:...

This Perspective Article highlights recent theoretical developments, and summarizes the current understanding of the photolytic properties of cobalamins from a computational point of view. The primary focus is on two alkyl cobalamins, methylcobalamin (MeCbl) and adenosylcobalamin (AdoCbl), as well as two non-alkyl cobalamins, cyanocobalamin (CNCbl) and hydroxocobalamin (HOCbl). Photolysis of al...

The elimination of ranitidine (a pharmaceutical compound) has been carried out in the presence of UV-C radiation. After some preliminary experiments, it has been experienced the no influence of the gas nature (air or oxygen) bubbled in photolytic experiments. From simple photolysis experiments the quantum yield of this compound has been determined. Two photolytic approximation has been used, th...

Photolytic uncaging of biologically-active molecules within cells is a powerful technique. However, the delivery of uncaging light into the cytosol can vary between cell types, individual cells of the same type, and different loci within an individual cell because of optical differences in absorbance and light-scattering properties of the cytoplasm. Here, we demonstrate a simple technique for m...

Piracetam was subjected to the hydrolytic, oxidative, thermal and photolytic stress, according to ICH guideline Q1A (R2). The drug depicted degradation only in basic conditions, while it was stable to other stress conditions (acidic, neutral hydrolysis, thermal and photolytic conditions). A total of one degradation product was formed, which were separated on a BEH column employing an isocratic ...

In the present study, photoinduced degradation of antidepressant drug sertraline under artificial solar radiation was examined. Photolysis studied different experimental conditions to explore its photolytic fate in aqueous environment. Photolytic kinetics were carried out ultrapure water, wastewater effluent, as well presence dissolved organic matter (humic acids), bicarbonate and nitrate ions ...

First-principles simulations suggest that additional OH formation in the troposphere can result from ozone interactions with the surface of cloud droplets. Ozone exhibits an affinity for the air-water interface, which modifies its UV and visible light spectroscopic signatures and photolytic rate constant in the troposphere. Ozone cross sections on the red side of the Hartley band (290- to 350-n...

BACKGROUND Asthma is characterized by airway hyper-responsiveness and variable airflow obstruction, in part as a consequence of hyper-contractile airway smooth muscle, which persists in primary cell culture. One potential mechanism for this hyper-contractility is abnormal intracellular Ca(2+) handling. METHODS We sought to compare intracellular Ca(2+) handling in airway smooth muscle cells fr...