Far red and near infrared (NIR) light promotes wound healing, but the mechanism is poorly understood. Our previous studies using 670 nm light-emitting diode (LED) arrays suggest that cytochrome c oxidase, a photoacceptor in the NIR range, plays an important role in therapeutic photobiomodulation. If this is true, then an irreversible inhibitor of cytochrome c oxidase, potassium cyanide (KCN), s...

Methanol intoxication produces toxic injury to the retina and optic nerve, resulting in blindness. The toxic metabolite in methanol intoxication is formic acid, a mitochondrial toxin known to inhibit the essential mitochondrial enzyme, cytochrome oxidase. Photobiomodulation by red to near-IR radiation has been demonstrated to enhance mitochondrial activity and promote cell survival in vitro by ...

Photobiomodulation (PBM) describes the use of red or near-infrared light to stimulate, heal, regenerate, and protect tissue that has either been injured, is degenerating, or else is at risk of dying. One of the organ systems of the human body that is most necessary to life, and whose optimum functioning is most worried about by humankind in general, is the brain. The brain suffers from many dif...

Ramsay-Hunt syndrome is an infectious disease associated with the varicella-zoster virus, and peripheral facial palsy often one of its clinical manifestations. This case report describes a patient diagnosed who developed was treated by photobiomodulation therapy. A 26-year-old woman lack mobility on right side, asymmetry, otalgia, dysgeusia, dry eyes, leading to diagnosis syndrome. Her classifi...

OBJECTIVE This review examines the evidence of neural inhibition as a mechanism underlying pain relief and anesthetic effect of photobiomodulation (PBM). BACKGROUND PBM for pain relief has also been used for more than 30 years; however, the mechanism of its effectiveness has not been well understood. METHODS We review electrophysiological studies in humans and animal models and cell culture...

Laser is considered basically effective for treating periodontal diseases because of its excellent physical properties namely ablation, hemostasis, bacterial killing and cell stimulation. The current laser application mainly used for the treatment of periodontitis is high-power laser ablation (HLLT). Laser ablation of diseased periodontal tissues using the HLLT is widely performed, partly expec...

At the end of 2013, The United Nations (UN) General Assembly 68th Session proclaimed 2015 to be the International Year of Light (IYL). Various scientific organizations, institutions, and societies are to all be brought together to raise global awareness about light (and lasers) and its uses in technology, including medicine, and everyday use. This worldwide program will highlight our dependence...

The biological effects of different wavelengths of light emitting diode (LED) light tend to vary from each other. Research into use of photobiomodulation for treatment of skin wounds and the underlying mechanisms has been largely lacking. We explored the histopathological basis of the therapeutic effect of photobiomodulation and the relation between duration of exposure and photobiomodulation e...