نتایج جستجو برای: pharmacokinetic properties

تعداد نتایج: 890912  

Journal: :Journal of Pharmacology and Experimental Therapeutics 2019

Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...

Journal: :Antimicrobial Agents and Chemotherapy 1986

Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...

Journal: :iranian journal of basic medical sciences 0
tamara aghebati pharmaceutical research centre, mashhad university of medical sciences, mashhad, iran mohsen foroughipour department of neurology, faculty of medicine, ghaem hospital, mashhad university of medical sciences, mashhad, iran mahmoud reza azarpazhooh department of neurology, faculty of medicine, ghaem hospital, mashhad university of medical sciences, mashhad, iran naghme mokhber department of psychiatry, faculty of medicine & psychiatric research centre, ebn-sina hospital, mashad university of medical sciences, mashhad, iran mohammad hasanzadeh khayat pharmaceutical research centre, mashhad university of medical sciences, mashhad, iran department of medicinal chemistry, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s) as there are conflicting findings regarding the clearance-dose and patient characteristics relationships for valproic acid (vpa), this study was conducted to investigate the relationship between patient demographic characteristics, vpa dosage and the drug clearance in adult iranian patients. materials and methods patients (n= 47) were either on monotherapy with vpa or were under co...

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