Thanks to developments in the field of nanotechnology over the past decades, more and more biosafe nanoscale materials have become available for use as pharmaceutical adjuvants in medical research. Nanomaterials possess unique properties which could be employed to develop drug carriers with longer circulation time, higher loading capacity, better stability in physiological conditions, controlle...

Transdermal administration of drugs has advantages over conventional oral administration or administration using injection equipment. The route of administration reduces the opportunity for drug evacuation before systemic circulation, and enables long-lasting drug administration at a modest body concentration. In addition, the skin is an attractive route for vaccination, because there are many ...

The use of gas-filled microbubbles in perfusion monitoring as intravascular ultrasound contrast agents has recently become more common. Additionally, microbubbles are employed as carriers of pharmaceutical substances or genes. Microbubbles have great potential to improve the delivery of therapeutic materials into cells and to modify vascular permeability, causing increased extravasation of drug...

The lung is an attractive target for drug delivery due to noninvasive administration via inhalation aerosols, avoidance of first-pass metabolism, direct delivery to the site of action for the treatment of respiratory diseases, and the availability of a huge surface area for local drug action and systemic absorption of drug. Colloidal carriers (ie, nanocarrier systems) in pulmonary drug delivery...

The use of hydrogels as carriers for protein delivery has been a subject of significant recent research. In our recent work, we have shown that diffusion controlled delivery of proteins from hydrogels containing poly(ethylene glycol) (PEG) can be possible and controlled by the three-dimensional structure. In addition, a number of these hydrogel carriers are mucoadhesive and can be used for prot...

Aim: Nano structured lipid carriers (NLCs) contains solid and liquid lipids as the significant principle in the drug delivery system. This review is focused on various aspects involved in the preparation, structure, advantages, limitations, types, physiochemical characterization and wide pharmaceutical applications of SLN has been explored. Method:It is revealed that NLCs proved to be a promisi...

Nanotechnology based Pharma has emerged significantly and has influenced the Pharma industry up to a considerable extent. Nanoparticles technology holds a good share of the nanotech Pharma and is significant in comparison with the other domains. Electrospraying technology answers the potential needs of nanoparticle production such as scalability, reproducibility, effective encapsulation etc. Ma...

UV induced skin damage by reactive oxygen species is a rapid process which can be averted by application of antioxidants at the onset or during the deve lopment o f ox idat i ve s t re s s . Ant iox idant supplementation is an integral part of a multi-faceted approach in photoprotection. Lipid based carriers have been more and more explored in pharmaceutical technology, showing superior advanta...

Macro biomolecules are of vital importance in regulating the biofunctions organisms, which proteins (including peptides when mentioned below) and nucleic acids (NAs) most important. Therefore, these NAs can be applied as “drugs” to regulate from abnormal normal. Either for NAs, challenging thing is avoid biodegradation or physicochemical degradation before they reach targeted location, then fun...

Abstract Drug transport in human body is often intensified by various carriers. The simplest and highly effective are emulsions. In these liquids, one phase dispersed other the form of droplets, which active substance dissolved. existing application such liquids as carriers, monodispersity systems has been a very important parameter, because when all droplets have same size, it relatively easy ...