Abstract Background: Attarasa (L.a cubeba (Lour.) Pers.) is a potential Indonesian medicinal plant that used as cold remedy, head ulcers, antimicrobials, antioxidants, and anticancer drugs. Objective: This research was conducted to analyze the immunomodulatory effect of bark (EEKBA) fruit attarasa ethanolic extract (EEBA) by detecting its phagocytosis activity in male mice using carbon clearanc...

OBJECTIVE Atopic dermatitis (AD) is a skin disorder clinically seen in the pediatric population. It is well recognized that patients with AD have an increased susceptibility to cutaneous colonization and infection with bacteria, fungi, and viruses. This study was undertaken to investigate the phagocytic activity and chemotactic response of mononuclear and polymorphonuclear leukocytes in severe ...

CD44, a transmembrane adhesion molecule involved in binding and metabolism of hyaluronan, has additional functions in inflammatory and immune responses, contributing to the ingestion and clearance of particles and apoptotic cells. Our goal was to determine the specific role of CD44 in phagocytosis and whether it functions as a primary or accessory phagocytic receptor. Using hyaluronan-coated be...

BACKGROUND/AIMS Renal ischaemia-reperfusion injury (IRI) is a systemic inflammatory process in which Th1 responses predominate affecting other organs including the lungs. The present study explored the phagocytic and microbicidal capacity of macrophages in rats with lung inflammation that underwent IRI. METHODS The alveolar macrophages of rats sensitised to OVA were evaluated for phagocytosis...

Murine thioglycollate-elicited peritoneal macrophages were cultured in the presence of a variety of fatty acids added as complexes with bovine serum albumin. All fatty acids tested were taken up readily by the cells and both neutral and phospholipid fractions were enriched with the fatty acid provided in the medium. This generated a range of cells enriched in saturated, monounsaturated or polyu...

OBJECTIVE Oxidative stress plays a critical role in the pathogenesis of atherosclerosis. The NADPH oxidase constitutes the main source of superoxide in phagocytic and vascular cells. This study aimed to investigate the levels of NADPH oxidase-mediated superoxide production in phagocytic cells and the association between phagocytic superoxide production and carotid intima-media thickness (IMT), ...

The effect of enrofloxacin and alfa tocopherol on the capacity of bovine milk leukocytes to generate reactive oxygen species and phagocytic activity after stimulation with phorbol 12-myristate 13-acetate (PMA) for superoxide were studied in bovine clinical mastitis. Group I, consisting of 9 healthy cows, served as the control, whereas groups II and III each contained 9 cows with clinical mastit...

PURPOSE The aim of this study was to evaluate the total blood platelets count, fraction of phagocytizing thrombocytes (PhT%), and phagocytic index of thrombocytes (PhIT) in gastric cancer considering the stage of the disease, and perioperative immunonutrition support. METHODS Our study included 44 patients operated for gastric cancer divided into 2 groups depending on the clinical stage, and ...