نتایج جستجو برای: peroxisome proliferator activated receptors

تعداد نتایج: 423823  

Journal: :Biochimie 2017
Valentin Barquissau Rayane A Ghandour Gérard Ailhaud Martin Klingenspor Dominique Langin Ez-Zoubir Amri Didier F Pisani

Oxylipins are bioactive metabolites derived from the oxygenation of ω3 and ω6 polyunsaturated fatty acids, triggered essentially by cyclooxygenase and lipoxygenase activities. Oxylipins are involved in the development and function of adipose tissue and their productions are strictly related to diet quality and quantity. Oxylipins signal via cell surface membrane (G Protein-coupled receptors) an...

Journal: :Bioorganic & medicinal chemistry letters 2000
D L Mohler G Shen A K Dotse

Solution- and solid-phase methods for the preparation of peptide-substituted thiazolidinediones have been developed as an approach towards the preparation of a library of these compounds as potential ligands for the peroxisome proliferator-activated receptors (PPARs).

2013
Caitlin Falconer Paraic A. Kenny Chanel E. Smart Gregory R Monteith Sarah J Roberts-Thomson

Background: Peroxisome proliferator-activated receptors (PPARs) have a pivotal role in regulating genes that are involved in lipid

Journal: :American journal of physiology. Heart and circulatory physiology 2005
Ernesto L Schiffrin

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that heterodimerize with the retinoid X receptor and then modulate the function of many target genes. Three PPARs are known: alpha, beta/delta, and gamma. The better known are PPAR-alpha and PPAR-gamma, which may be activated by different synthetic agonists, although the endogenous ligands are unknown. PPAR-alpha is invol...

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