Two simple and sensitive kinetic methods were developed for the determination of ribavirin in bulk and in its pharmaceutical preparations using alkaline potassium permanganate as an oxidizing agent. The methods are based upon a kinetic investigation of the oxidation reaction of the drug at room temperature for fixed times of 20 and 30 minutes. In the first method, the absorbance of the colored ...

As the result of some experience in the determination of lactic acid in blood, muscle, and solutions of sugar derivatives, we have introduced various modifications in the process by which it gains considerably in simplicity, speed, convenience, and reliability. The basis of the method is the oxidation of the lactic acid in boiling sulfuric acid solution to acetaldehyde by permanganate (l), aera...

A sensitive kinetic method for spectrophotometric determination of acarbose is developed and validated for the determination of the drug in bulk and pharmaceutical formulations. The drug was estimated in simulated gastrointestinal media i.e., 0.1 M HCl (pH 1.2) and phosphate buffer (pH 6.8). The method involves the oxidation of acarbose by treating it with a strong oxidizing agent (potassium pe...

In this study we investigated the enrichment ability of oxidized multiwalled carbon nanotubes (MWCNTs) and established a new method for the determination of trace cadmium in environment with flame atomic absorption spectrometry. The MWCNTs were oxidized by potassium permanganate under appropriate conditions before use as preconcentration packing. Parameters influencing the recoveries of target ...

The standard procedure for the determination of chlorine in organic compounds of mercury consists in decomposition of the material, separation of mercury and determination of chlorine as chloride. Decomposition of the sample could be achieved by wet mineralization [1,2], ignition in a stream of oxygen [3—7] or nitrogen [8], ignition in a flask with oxygen [9], etc. [10, 11]. Chlorine and mercur...