conclusions our results support the use of pns in some patients with refractory chronic headaches. appropriate surgical planning and technique are important to achieve good clinical outcome and to minimize complications. background subcutaneous peripheral nerve stimulation (pns) has emerged as a useful tool in the treatment of intractable headaches. however, complications such as skin erosion, ...

excessive scarring; paralleling the process in tendon reconstruction of the hand. inspired by the advantages of the two-stage technique in tendon grafting and with encouraging preliminary results, we aimed to investigate the two-stage nerve grafting technique as an alternative method of secondary nerve repair. methods:  thirty female rats (~200 g) were randomly distributed into two groups (n=15...

Peripheral nerve injury is a common and devastating complication after trauma and can cause irreversible impairment or even complete functional loss of the affected limb. While peripheral nerve repair results in some axonal regeneration and functional recovery, the clinical outcome is not optimal and research continues to optimize functional recovery after nerve repair. Cell transplantation app...

Introduction: Repair of peripheral nerve injuries is an intensive area of challenge and research in modern reconstructive microsurgery. Intensive research is being carried out to develop effective alternatives to the standard nerve autografting, avoiding its drawbacks. The aim of the study was to evaluate the effectiveness of a newly designed mechanical device for the reconstruction of the...

6 " Modulated expression of antioxidant molecules during peripheral nerve regeneration " C. 7 " Comparative proteomic profile of rat sciatic nerve and gastrocnemius muscle tissues in ageing by 2‐D DIGE " D. 8 " Inhibition of RhoA promotes peripheral axon regeneration " 9 " JNK‐AP1 pathway is involved in axonal growth potential and neuroregulation of CGRP dynamics in mice DRG after peripheral ne...

objective: as effectiveness of the autologous graft in the repair of long nerve defects is very limited an effective substitute is needed. this study was conducted to determine the poled polyvinylidene fluoride (pvdf) tube as an alternative to nerve autograft. materials and methods: the left sciatic nerve was transected in 45 male wistar rats. the animals were then divided randomly into three g...

Peripheral nerve injury can have a potentially devastating impact on a patient's quality of life, resulting in severe disability with substantial social and personal cost. Refined microsurgical techniques, advances in peripheral nerve topography, and a better understanding of the pathophysiology and molecular basis of nerve injury have all led to a decisive leap forward in the field of translat...

background: many people suffer from nerve injury. the time consuming nature of the treatments makes the condition worse. therefore, finding a way to accelerate the process of nerve repair is very important. objective: to determine the effect of ultrasound on the acceleration of crushed peripheral nerve regeneration. methods: the experimental model included crushed rat’s sciatic nerve. 40 rats w...