The cytogenetic effect of low-dose gamma irradiation on the heredity structures of rabbits was studied. Rabbit peripheral blood lymphocytes were irradiated in vitro within the dose range 0.25-1.0 Gy on Rokus equipment with Со radiation source at a dose rate of 2.22 cGy/s. The analysis of cytogenetic data showed that the frequency of induced chromosomal aberrations in rabbit peripheral blood lym...

Abstract Background Venous thromboembolism (VTE) is a frequent complication in cancer patients and often detected as asymptomatic peripheral deep vein thrombosis (DVT). However, guidelines for DVT have not been established either general cardiology or onco-cardiology. Furthermore, patients, it generally considered difficult to administer standard doses of anticoagulants due the high risk bleedi...

diabetes mellitus is a metabolic disorder affecting carbohydrate, fat and protein metabolism that affects nearly 10% of the population every year. the treatment of diabetes mellitus has been confined to use of oral hypoglycemic agents and insulin, the former being reported to possess serious side effects. this leads to increasing demand for herbal products with antidiabetic factor with little s...

background: induction of radioadaptive responses in cells pretreated with a low dose radiation before exposure to a high dose is well documented by many investigators. the aim of this study is to determine the frequency of chromosomal aberration in peripheral blood lymphocytes of patients treated by radioiodine (131i) for hyperthyroidism, with or without previous thyroid scan with 99mtc. materi...

objective: acute inflammatory demyelinating peripheral neuropathy (guillain-barre-syndrome) is by far the most common cause of immune-medicated peripheral nervous system disease in children; with the near disappearance of poliomyelitis, gbs is responsible for the great majority of cases of acute flaccid paralysis. so far, in several controlled studies, corticosteroids, plasmapheresis and ivig h...

OBJECTIVE We are conducting an open-label phase 1b study on the efficacy of intrathecal (IT) administration of rituximab, provided via an Ommaya reservoir, for the treatment of progressive multiple sclerosis (PMS). The objective of this initial study was to monitor B lymphocytes in peripheral blood (PB) and CSF from the first 10 patients 1 year posttreatment. METHODS Dose titration was perfor...