The literature reports an annual incidence of 5,900 cases of anal cancer in the developed countries. These involve three different anatomic zones: carcinoma of the anal canal, perianal carcinoma (formerly known as carcinoma of the anal margin, located at a distance of less than 5cm from the anal margin), and carcinoma of the perianal skin (at a distance greater than 5cm from the anal margin). B...

We report a 2 year 6 months old girl suffering from HIV infection and presenting with two giant condyloma acuminata of perianal and perivulvar region along with oral candidiasis.

Benign apocrine lesions have been described in the anogenital region, although according to the World Health Organisation convincing examples of anal apocrine adenocarcinomas have not been published. This report describes the case of an invasive apocrine adenocarcinoma arising in a benign adenoma in the perianal region of a 45 year old woman. The origin and invasiveness are supported by histolo...

The appearance of cutaneous metastases in the perianal region from adenocarcinoma of colon and rectum is an uncommon feature, and its presence usually implies a worse prognosis as a disseminated disease. Occasionally, they present with no evidence of visceral involvement, therefore their diagnosis and treatment can significantly modify the course of the disease. We present 3 patients with peria...

INTRODUCTION Verrucous carcinoma of the external genitalia and perianal region is a rare variant of well-differentiated squamous cell carcinoma. It has been reported to have limited metastatic potential. CASE PRESENTATION We report the case of a 54 year-old Moroccan man who presented with locally advanced giant condyloma acuminatum (Buschke-Löwenstein tumor) after prolonged intervals of negle...

Abstract Background The anal and perianal region is an anatomically complex region. differential diagnosis for masses broad can represent both benign malignant lesions. Case Presentation We present the case of a 63-year-old gentleman who presented to outpatient clinic with large mass which had been one year. was increasing in size becoming painful. He did not report any alterations bowel habit,...

Pilonidal disease typically presents with an abscess or intermittent pain and drainage in the sacrococcygeal region during the pubertal years. Further examination typically reveals pits in the midline of the sacrococcyx area due to entrapment of hair with recurrent entrapment, infection, and drainage. The following paper describes an unusual presentation of a pilonidal cyst with fissure and per...

BACKGROUND We examined the baseline prevalence of penile, scrotal, and perineal/perianal human papillomavirus (HPV) in heterosexual men (HM). We also evaluated baseline characteristics of HM to assess factors associated with prevalent HPV detection. METHODS We tested serum samples from 3463 HM aged 16-24 years with 1-5 lifetime female sexual partners for antibodies to HPV 6, 11, 16, and 18. W...

The purpose of this study was to evaluate the safety and efficacy of ANOAC topical cream in the management of perianal symptoms due to anal fissure and hemorrhoids. Adult patients with perianal symptoms were enrolled in the study. Patient applied Anoac cream twice a day for 60 days. Perianal symptoms like anal pain, swelling, itching, burning and pricking sensation were evaluated on the visual ...