Industrial organizations are complex systems` where the interactions among the various functions such as Sales, Distribution, Manufacturing, Materials, Finance, Human Resources and Maintenance have to be man-aged towards a common purpose of delivering the customers satisfaction. However, since most of these or-ganizations have a `Functional Structure`, each function or department works towards ...

A Phase I study of pentamethylmelamine (PMM) was conducted, administering the drug as a 24-hr i.v. infusion once weekly for 3 weeks. Doses ranged from 80 to 3000 mg/sq m/week. Twenty-six evaluable patients received a total of 30 courses of PMM. The median performance status of the patients was 60% (range, 40 to 90%), and the median age was 58 years (range, 43 to 72 years). The highest tolerated...

Phosphomannomutase (PMM; EC 5.4.2.8) is a cytosolic enzyme that catalyzes the reversible conversion of mannose 6-phosphate to mannose 1-phosphate, a substrate for the synthesis of GDP-mannose, which is a nucleotide sugar required in glycosylation. Previously known in yeast (1, 2), Van Schaftingen and Jaeken (3 ) described the enzyme in 1995 in humans and its deficiency in patients with congenit...

This paper proposes an innovative Pipelinebased Maximal-sized Matching scheduling approach, called PMM, for input-bu ered switches. It dramatically relaxes the limitation of a single time slot for completing a maximal matching into any number of time slots. In the PMM approach, arbitration is operated in a pipelined manner, where K subschedulers are used. Each subscheduler is allowed to take mo...

A mobile agent is a promising area in distributed systems. It is a new technology for computers to communicate. Despite the multiple benefits of the mobile agent, but there are several obstacles to its spread. The mobile agent protection is one of these obstacles. In this paper a new mechanism has been proposed to protect mobile. The mechanism is called Partial-Mobility Mechanism (PMM). The mai...

Predictive analytics (PA) is a popular approach to support managerial decision making. The core of a PA-based decision aids consists of an empirical prediction model. It is common to create such models using statistical standard methods. We argue that this approach suffers from a partial modelling mismatch (PMM) because the internal (statistical) objective of the decision support model and the ...

regarding to rapidly changing and highly competitive business environment it will become increasingly important for organizations to measure their performances appropriately. with respect to special characteristics of pharmaceutical industry and lack of reported performance measurement, this study tries to design an integrated performance measurement model for pharmaceutical companies. for gene...

Software development processes such as the Waterfall process and Extreme Programming are Project Management Methods (PMMs) which are well known and widely used. However, conventional Project Management (PM) lacks the process concepts expressed in PMMs, and the connection between PMMs and PM is not much explored in the literature. Our research problem is to make this connection. We present data ...

We have previously shown that histone H3 is transiently phosphorylated at Thr3 during mitosis. Extending these studies, we now report that phosphorylated Thr3 is always in cis to trimethylated Lys4 and dimethylated Arg8, forming a new type of combinatorial modification, which we have termed PMM. PMM-marked chromatin emerges at multiple, peripheral sites of the prophase nucleus, then forms disti...