In this study, the author examined the cross-reactivities of Stachybotrys chartarum, Aspergillus niger/fumigatus, and Penicillium notatum with affinity-purified rabbit sera. The molds were grown for expression of maximum numbers of antigens, after which they were extracted and mixed with commercially available extracts. The mixture was used for antibody preparation in rabbits, measurement of an...

A 65-year-old Japanese male had severe bronchial asthma had increased mold-containing sputum. Serum total IgE level had increased to 798 IU/mL and antigen-specific precipitating antibodies to P. luteum and P. notatum were present but not those reactive toward any species of Aspergillus. Chest computed tomography revealed central bronchiectasis and bronchial wall thickness. After antigen-specifi...

In this paper, following corrections should be made: (page 336, Fig. 4) Replace the figure as follows: (page 336, legend of Fig. 4, line 2) For " S-125 " Read " S-128 " (continues to the next page)

Foster, McDaniel, Woodruff, and Stokes (1945) recently described the formation of conidia by molds of the genus Penicillium during submerged growth in liquid culture media. Controlling or associated factors for this phenomenon were described as the presence of a rather high calcium-ion concentration and, in general, the development of considerably less mycelium before spore formation than is fo...

The aim of this study was to investigate the prevalence of fungal sensitization and to detect the IgE and eosinophilic cationic protein (ECP) levels in the positive cases inhabiting in Kocaeli province (located in Northwest region of Turkey). The results of mixed fungus tests of 1.799 patients (870 male, 929 female) ages between 3-80 years old who were admitted to Kocaeli University Medical Fac...

Fungi comprise a vast group of microorganisms including the Ascomycota (majority of all described fungi), the Basidiomycota (mushrooms or higher fungi), and the Zygomycota and Chytridiomycota (basal or lower fungi) that produce industrially interesting secondary metabolites, such as β-lactam antibiotics. These compounds are one of the most commonly prescribed drugs world-wide. Since Fleming's i...

The mould genus, Penicillium, is a significant source of environmental aero-allergens. A major allergen from Penicillium notatum, Pen n 18, was identified by two-dimensional immunoblotting using monoclonal antibody G11A10, raised against the vacuolar serine protease of Penicillium citrinum, followed by matrix-assisted laser-desorption ionization-time-of-flight MS analysis of the peptide digest....