نتایج جستجو برای: penfluridol

تعداد نتایج: 60  

2015
Carolin Lübker Roland Seifert

Adenylyl cyclases (ACs) catalyze the conversion of ATP into the second messenger cAMP. Membranous AC1 (AC1) is involved in processes of memory and learning and in muscle pain. The AC toxin edema factor (EF) of Bacillus anthracis is involved in the development of anthrax. Both ACs are stimulated by the eukaryotic Ca(2+)-sensor calmodulin (CaM). The CaM-AC interaction could constitute a potential...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2002
Celia M Santi Francisco S Cayabyab Kathy G Sutton John E McRory Janette Mezeyova Kevin S Hamming David Parker Anthony Stea Terrance P Snutch

T-type calcium channels play critical roles in cellular excitability and have been implicated in the pathogenesis of a variety of neurological disorders including epilepsy. Although there have been reports that certain neuroleptics that primarily target D2 dopamine receptors and are used to treat psychoses may also interact with T-type Ca channels, there has been no systematic examination of th...

2005
DAPHNE C. ELLIOTT

Two classes of compous which bind to calnodulin in a calciumdependent manner (neuroleptic drugs and local anaesthetics) were used to investigate the possible involvement of a calcium-dependent regulator protein in the action of the plant hormones cytokinins. The cytokinin-induced synthesis of betacyanin in Amarandus tricolr seedlings was used as one test system. The calmodulin antagonists inhib...

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