one of the most valid and efficient models of long rod projectile penetration in homogeneous targets is tate and alekseevskii’s (a&t;) model. based on tate’s model, the present research tries to calculate the optimum speeds to achieve the maximum penetration depth in the homogeneous targets. the proposed collision speed-penetration depth diagrams are developed using tate’s model. in this way, v...

Limited efficacy of chemotherapeutic drugs against solid tumors has been attributed to poor drug penetration into tumor tissues. Multicellular layer (MCL) cultures recapitulate barriers to drug penetration and distribution and have been used successfully in the production of clinically relevant data. In the present study, we evaluated the characteristics of paclitaxel (PTX) and 5-fluorouracil (...

piroxicam is a non-steroidal anti-inflammatory agent which has an extensive use in rheumatic disorders. since its skin penetration is still a subject for research, the aim of this study was to evaluate the effect of dimethyl sulfoxide on percutaneous penetration of piroxicam gel formulation through skin. in this study, as a model, two types of 0.5% piroxicam new gels, so called red and green ge...

This paper presents a modified form of the Walker-Anderson (W-A) model for analyzing high velocity penetration of an eroding projectile into a concrete target in which the W-A model is improved by incorporating calculations for the plastic flow field of concrete in terms of its compressibility and strain rate sensitivity under severe pressure. With the changes to and calculations of plastic fie...

According to literature, penetration pricing is the dominant pricing strategy for network effect markets. In this paper we show that diffusion of products in a network effect market does not only vary with the set of pricing strategies chosen by competing vendors but also strongly depends on the topological structure of the customers' network. This stresses the inappropriateness of classical "i...