A positive association between nephrolithiasis and blood pressure has been suggested in previous studies. However, controversy remains, due to methodological problems in some of the previous studies and absence of prospective data. We evaluated the relationship between nephrolithiasis and the risk of hypertension in a cohort of 51,529 men followed prospectively for 8 years. Information was obta...

Cystinuria is an inherited disorder characterized by defective renal reabsorption of cystine and dibasic amino acids leading to nephrolithiasis. This study was conducted to analyze the genotypes and phenotypes of pediatric patients with cystinuria. Eight children from Seoul National University Hospital and Asan Medical Center presenting with cystinuria from January 2003 to June 2016 were retros...

Much has changed since the launching in the US of the EndStage Renal Disease (ESRD) Program under Medicare on July 1, 1973, a unique entitlement program based solely on the presence of a clinical condition. Dialysis, initially a privilege for a select few, has exploded since then to become a multibillion dollar industry today, with over 600,000 patients on dialysis in the US, and over 1.6 milli...

Conclusion: Nephrolithiasis remains a major economic and health burden worldwide. Nephrolithiasis is considered a systemic disorder associated with chronic kidney disease, bone loss and fractures, increased risk of coronary artery disease, hypertension, type 2 diabetes mellitus, and the metabolic syndrome. Further understanding of the pathophysiological link between nephrolithiasis and these sy...

Background: We sought to assess the strength of the evidence for long-term lemonade therapy on urinary citrate excretion and stone formation in patients with hypocitraturic nephrolithiasis. Context of the study: A literature search was conducted via PubMed (1970–June 2015) using the key terms “lemonade” and “hypocitraturic nephrolithiasis,” as well as the Medical Subject Headings “medical thera...

In humans, ammonium urate (AU) nephrolithiasis is rare in the Western hemisphere and more common in Japan and developing countries. Among a variety of risk factors, insulin resistance has been associated with urate nephrolithiasis in people. Bottlenose dolphins (Tursiops truncatus) are susceptible to AU nephrolithiasis, and it is believed that some populations are more likely to develop nephrol...

INTRODUCTION Nephrolithiasis is a common multifactorial kidney disease with worldwide distribution. Compelling evidence, regarding the function of kidney in maintaining the body homeostasis, suggests the role of oxidative stress in the pathogenesis of nephrolithiasis. Glutathione peroxidase 1 is a major antioxidant enzyme, preventing oxidative damage to renal cells by detoxifying hydrogen and l...

Abstract Background The first wave of the COVID-19 pandemic in March 2020 forced our healthcare system Bronx, New York to cancel nearly all scheduled surgeries. We developed a framework for prioritizing postponed urologic surgeries that was utilized once cases were permitted be rescheduled. As many parts country experience and second waves this pandemic, may serve as resource other centers expe...