protein losing enteropathy (ple) as an initial finding of lymphoma, is extremely rare in childhood. we describe clinical and pathological features of an unusual case of gastrointestinal lymphoma presented with ple as a sole manifestation. differential diagnosis in children presenting with ple is critical because early diagnosis and treatment are important for survival in patients with lymphoma.

background and objective: since there are very few studies on the immunodeficiency state of the iranian survivors of pediatric acute lymphoblastic leukemia (all), we conducted this study to determine the prevalence of humoral defects in children with all at least one year after completion of chemotherapy. methods: in this study, antibody titers for mumps, rubeola, rubella, tetanus and diphtheri...

lipoma arborescens, also known as villous lipomatous transformation of synovium is an unusual fatty lesion of joint. this disorder is characterized by a diffuse increase in the quantity of subsynovial fat in supra-patellar region which bulges the overlying synovial lining and produces a villous architecture. hereby we report a case of lipoma arborescens in an eleven year old boy with a history ...

background: acute myeloid leukemia (aml) is a malignant disorder involving blood cells, characterized by obstructed or distorted differentiation of hematopoietic stem cells. in cytogenetically normal aml (cn aml), molecular abnormalities in npm, flt3, cebpa, and baalc genes are observed. initially, high baalc (brain and acute leukemia cytoplasmic gene) expression was introduced in a study on am...

abstract background immune thrombocytopenic purpura (itp) is the most prevalent cause of thrombocytopenia in children. despite the importance of itp in children under 2- years old, only a few publications are available in the literature. itp usually presents itself as   isolated thrombocytopenia and mucocutaneous bleeding. materials and methods this study was conducted on 187 under 2- year-old ...

background: clinical reasoning process leads clinician to get purposeful steps from signs and symptoms toward diagnosis and treatment. this research intends to investigate the effect of teaching clinical reasoning on problem-solving skills of medical students.   methods: this research is a semi-experimental study. nineteen medical student of the pediatric ward as case group participated in a tw...

background brain abscess is an infrequent complication of meningitis, including cases caused by gram-negative enteric bacteria and klebsiella in neonates. brain abscess in neonates associated with high morbidity and mortality.recently, incidence of the disease is increasing because of increased predisposing factors. patients and method three cases of brain abscess in neonates are reported, 2 of...

objectives: midazolam with variable dosages has been used to induce sedation in pediatric dentistry. the aim of this study was to compare the efficacy of two dosages of oral midazolam for conscious sedation of children undergoing dental treatment. materials and methods: in this randomized crossover double blind clinical trial, 20 healthy children (asa i) aged three to six years with negative or...

trauma is the most common cause of mortality and morbidity in pediatric population. caring for the injured child requires special knowledge, precise management, and scrupulous attention to details. all clinicians who are responsible for the care of a pediatric trauma patient, including pediatricians, pediatric emergency room clinicians, and trauma surgeons, must be familiar with every tenet of ...