We introduce a way of implementing physically-based renderers that can switch rendering methods with raytracing library. Various (PBR) generate beautiful images are close to human view real world. However, comparison between corresponding pairs pixels image generated by different is necessary verify whether the implementation correctly obeys mathematical models PBR. For comparison, result must ...

This paper presents the results of case studies that were carried out aiming at evaluating the defects identified by GUCCRA application and PBRUser application. GUCCRA – Guidelines for Use Case Construction and Requirements document Analysis – is a set of two reading techniques that helps the elaboration of Use Case Model and, simultaneously, identifies defects in the Requirements Document. The...

BACKGROUND The peripheral-type benzodiazepine receptors (PBR) are localized on the outer mitochondrial membrane, as a constituent of mitochondrial permeability transition (MPT)-pore. Among its hypothesized functions, the regulation of the mitochondrial respiratory chain and apoptosis have been suggested; in addition alterations of PBR site density have been shown in some neuropathologic conditi...

Cancer cell-derived micro-particles (MPs) play important regulatory roles on cellular and system levels. These activities are attributed in part to protein factors carried by MPs. However, recruitment strategies for sequestering certain protein factors in MPs are poorly understood. In the current study, using exogenous and endogenously expressed phospholipid-binding probes, we investigated the ...

The peripheral-type benzodiazepine receptor (PBR) is involved in many cellular functions, including steroidogenesis, oxidative processes, cellular proliferation, and apoptosis. Secretory and glandular tissues, especially steroid hormone-producing cells, are particularly rich in PBR. To understand the mechanisms of PBR expression and regulation, we established an mRNA expression profile in mouse...

The effects of PK11195, a high-affinity peripheral benzodiazepine receptor (PBR) ligand, on protein phosphorylation in isolated purified rat brain mitochondria were investigated. The isoquinoline carboxamide ligand of PBR, PK11195, but not the benzodiazepine ligand Ro5-4864, in the nanomolar concentration range strongly increased the phosphorylation of 3.5 and 17 kDa polypeptides. The effect of...

The basic motivation for software inspections is to detect and remove defects before they propagate to subsequent development phases where their detection and removal becomes more expensive. To maximize this potential, the examination of the artefact under inspection must be as thorough and detailed as possible. This implies the need for systematic reading techniques that tell inspection partic...

Introduction Since 2003/04 the Department of Health (DH) has been progressively implementing a prospective payment casemix funding system, known as Payment by Results (PbR), so that in 2008/09 over 90 percent of acute inpatient activity is reimbursed through PbR. The accuracy of the data recorded for each episode of care can directly influence the accuracy of reimbursement between commissioners...

Peripheral-type benzodiazepine receptor (PBR) is an 18-kDa high-affinity cholesterol and drug ligand-binding protein involved in various cell functions, including cholesterol transport and steroid biosynthesis. To aid our investigation of the biological function of PBR, we have set out to identify functional antagonists. By screening phage display libraries, we have identified peptides that dis...

The peripheral benzodiazepine receptor (PBR) is a critical component of the mitochondrial permeability transition pore, which is involved in the regulation of cell death. In the present study we investigated the role of PBR in the regulation of signaling pathways leading to apoptotic and necrotic damage and renal dysfunction in a rat model of ischemia-reperfusion. Renal ischemia-reperfusion led...