Induction of Drug-Metabolizing Enzymes by Fractionated Commercial Polybrominated Biphenyls (PBBs). ROBERTSON, L., PARKINSON, A., AND SAFE, S. (1981). Toxicol. Appl. Pharmacol. 57, 254-262. A commercial polybrominated biphenyl mixture was separated chromatographically into two fractions on neutral alumina (AA and A,) and into three fractions on Florisil (FA, Fa, and Fc) by sequential elution wit...

BACKGROUND Alteration in menstrual cycle function is suggested among rhesus monkeys and humans exposed to polybrominated biphenyls (PBBs) and structurally similar polychlorinated biphenyls (PCBs). The feedback system for menstrual cycle function potentially allows multiple pathways for disruption directly through the hypothalamic-pituitary-ovarian axis and indirectly through alternative neuroen...

Thyroid hormones, which influence body metabolism and development, could be affected by persistent organic pollutants. We sought to examine the relationship between polybrominated biphenyls (PBBs) and polychlorinated biphenyls (PCBs) and thyroid disease. We employed incidence density sampling to perform a nested case control analysis of the Michigan Long-Term PBB Cohort. Cohort members (n=3333)...

Context. Our Galaxy is composed of different stellar populations with varying chemical abundances, which are thought to imprint the composition planet building blocks (PBBs). As such, properties stars should affect planets and small bodies formed in their systems. In this context, high-resolution spectroscopic surveys open a window into links between host stars. Aims. We aim determine PBB trend...

In a Congressionally mandated study carried out under the aegis of the U.S. Agency for Toxic Substances and Disease Registry (ATSDR) and summarized in this article, the authors have provided estimates of the numbers of American women of childbearing age and the numbers of American pregnant women whose lead exposure is sufficiently elevated to pose an intrauterine toxicity risk. Exposures associ...