to evaluate long term safety and efficacy of the photo refractive keratectomy (prk) in myopic eyes with thin cornea, this study has been designed. in this retrospective case series study, we included 74 eyes of 38 myopic patients with preoperative central corneal thickness (cct) less than 550 micrometer who underwent for prk surgery prior to 2010 and had 4 years of mean follow up postoperativel...

background: lennox-gastaut syndrome (lgs) is an epileptic encephalopathy, characterized by drug-resistant multiple seizure types. the aim of this study was to determine if the adjunctive use of electroconvulsive therapy (ect) in patients with lgs and drug-resistant epilepsy is efficacious in decreasing their seizure frequency and also to investigate its safety and tolerability.   methods: this ...

conclusions the results demonstrated that the mortality rate was higher in cf patients with a positive family history, a consanguineous marriage, and residence in a rural area. therefore, demographic factors play an important role in the outcome of cystic fibrosis. unfortunately, these parameters, which can be managed easily and with low cost, have been overlooked. patients and methods this was...

This white paper lays out some foundational information about different approaches to safety: how various industries differ in their approaches to safety engineering, and a comparison of three general approaches to safety (system safety, industrial safety engineering, and reliability engineering). An attempt is made to lay out the properties of industries and systems that make one approach more...

Safety case development is not a post-development activity, rather it should occur throughout the system development lifecycle. The key components in a safety case are safety arguments. Too often, safety arguments are constructed without proper reasoning. Inappropriate reasoning in safety arguments could undermine a system’s safety claims, which in turn contributes to safety-related failures of...

purpose: to report and evaluate the characteristics of patients referred to the emergency department of labbafinejad medical center with work-related eye injuries during 2005.  methods: in this descriptive study, an available sample of patients with work-related eye injures were assessed. demographic characteristics, causes of ocular trauma, and use of work safety devices were main evaluated va...

background: patient safety is a serious global public health issue. estimates show that every day many patients are harmed while receiving hospital care. health care staff plays a key role in providing quality and safe patient care, especially physicians who are main members of the medical team and a critical element in patient safety efforts. objective: the current study used a theory of plann...

objectives: saffron is the stigma of crocus sativus l., which has the potentials to play a role in the treatment of many diseases. although many researches are now going on this precious spice, there are few data on saffron safety in human, especially in patients with chronic mental illnesses. this study aimed to evaluate the short-term safety and tolerability of both saffron and crocin (its ma...