BACKGROUND High risk human papillomavirus (HR HPV) infects cells at the squamocolumnar junction (SCJ) of the cervix, causing cancer. Cytokeratin (CK)7 is an SCJ marker, and stains cervical neoplasia. CK19 is a binding partner of CK7 and expressed in cervical cancer. Despite this possible association between CK7/CK19 and cervical cancer, not much is known about the mechanism of CK7/CK19 involvem...

Abstract Stochastic fluctuations of the neutron population within a nuclear reactor are typically prevented by operating core at sufficient power, since deterministic (i.e., exactly predictable) behavior is required automatic safety systems to detect unwanted power excursions. In order characterize conditions which vanish, an experiment was designed and took place in 2017 Rensselaer Polytechnic...

1. Kanitakis J, Lora V. Pagetoid dyskeratosis: A frequent pitfall in dermatopathology. Eur J Dermatol. 2010;20:123--4. 2. Toyonaga E, Inokuma D, Abe Y, Abe R, Shimizu H. Pagetoid dyskeratosis with parallel ridge pattern under dermoscopy. JAMA Dermatol. 2013;149:109--11. 3. Frenk E, Delacrétraz J. Hydropic degeneration of epidermal keratinocytes. An alteration leading to patchy hyperpigmentation...

Injections of neural tracers into many mammalian neocortical areas reveal a common patchy motif of clustered axonal projections. We studied in simulation a mathematical model for neuronal development in order to investigate how this patchy connectivity could arise in layer II/III of the neocortex. In our model, individual neurons of this layer expressed the activator-inhibitor components of a G...

1. Kanitakis J, Lora V. Pagetoid dyskeratosis: A frequent pitfall in dermatopathology. Eur J Dermatol. 2010;20:123--4. 2. Toyonaga E, Inokuma D, Abe Y, Abe R, Shimizu H. Pagetoid dyskeratosis with parallel ridge pattern under dermoscopy. JAMA Dermatol. 2013;149:109--11. 3. Frenk E, Delacrétraz J. Hydropic degeneration of epidermal keratinocytes. An alteration leading to patchy hyperpigmentation...

Most studies on the dynamics of recurrent cortical networks are either based on purely random wiring or neighborhood couplings. Neuronal cortical connectivity, however, shows a complex spatial pattern composed of local and remote patchy connections. We ask to what extent such geometric traits influence the "idle" dynamics of two-dimensional (2d) cortical network models composed of conductance-b...

Between 1996 and 2002, 162 cases of pulmonary melioidosis were reported from Srinagarind Hospital, Khon Kaen, northeast Thailand, 90 acute vs 72 subacute/chronic. Patients averaged 50 years of age and half worked as farmers. The male to female ratio was between 2 and 3 to 1 depending on the subgrouping. Burkholderia pseudomallei was confirmed by a culture or a four-fold rise in titer in the maj...

Integrin A5B1 is overexpressed on endothelial cells of tumor vessels and is uniformly and rapidly accessible to antibodies in the bloodstream. Here, we determined whether antibodies rapidly gain access to integrin overexpressed on the abluminal (basolateral) surface of endothelial cells through vascular leakiness or whether the rapid accessibility results instead because the integrin is overexp...