نتایج جستجو برای: patch mass

تعداد نتایج: 517276  

Journal: :Journal of analytical toxicology 2004
Naoto Uemura Rajneesh P Nath Martha R Harkey Gary L Henderson John Mendelson Reese T Jones

Sweat collection patches are used for drug abuse monitoring. We investigated the effect of sweat patch location (back and shoulder) on cocaine levels after controlled intravenous cocaine exposure (210 mg/70 kg) in 12 subjects (Experiment 1). Gas chromatographic-mass spectrometric analyses show cocaine and metabolites levels in Pharmchek trade mark patches were eightfold higher on the back than ...

2017
Chao Zhang Haiyan Li Xin Xiong Suodi Zhai Yudong Wei Shuang Zhang Yuanyuan Zhang Lin Xu Li Liu

We investigated the pharmacokinetics and safety profiles of a newly developed combined ethinylestradiol (EE)/gestodene (GSD) transdermal contraceptive patch after a single-dose administration and compared with the market available tablet formulation in healthy adult subjects. An open-label, two-period comparative study was conducted in 12 healthy women volunteers. A single dose of the study com...

2017
Je Hoon Park Il Gyu Ko Sung Eun Kim Jun Jang Jin Lakkyong Hwang Chang Ju Kim Soo Hwan Yoon Jongki Hong Jun Young Chung Deok Won Lee

PURPOSE Dexmedetomidine, an α2-adrenergic agonist, provides sedative and analgesic effects without significant respiratory depression. Dexmedetomidine has been suggested to have an antiapoptotic effect in response to various brain insults. We developed an oral mucosa patch using dexmedetomidine for sedation. The effects of the dexmedetomidine oral mucosa patch on cell proliferation and apoptosi...

2005
MATTEO GRIGGIO FRANCISCO VALERA ANDREA PILASTRO

Recent evidence suggests that female ornaments in birds not only are genetic correlates of selection on males but may also have evolved by selection acting directly on females. However, most evidence comes from studies in captivity and it is therefore still debated whether male choice is important under natural conditions. The rock sparrow, Petronia petronia, is a monomorphic passerine in which...

Journal: :Clinical chemistry 2004
Takeshi Saito Abraham Wtsadik Karl B Scheidweiler Neil Fortner Sanae Takeichi Marilyn A Huestis

BACKGROUND A sensitive gas chromatography-negative ion chemical ionization mass spectrometry (GC/MS-NICI) method was developed and validated for the measurement of Delta(9)-tetrahydrocannabinol (THC) in human sweat patches. METHODS THC-d(0) and THC-d(3) were added to worn blank sweat patches (PharmChek; PharmChem Incorporated) and extracted with 3 mL of methanol-0.2 mol/L sodium acetate buffe...

Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

Journal: :مهندسی عمران فردوسی 0
علیرضا کردجزی فریدون پویانژاد فرزاد شهابیان

the support vector machine (svm) is a relatively new machine learning method which is increasingly being applied to engineering problems and have yielded encouraging results. because of complex behavior of elastoplastic of web panels of plate girders under patch loading, almost none of the proposed methods provides consistent and accurate predictions of patch load capacity. consequently, altern...

2017
A. Singh M. Wyatt M. Clarke L. Wales

Introduction BioGlue (CryoLife Inc., Kennesaw, GA) is a commonly used surgical adhesive, designed to achieve haemostasis following large vessel cardiovascular operations. Report An 88-year-old female presents with an enlarging right sided neck mass 9 months after carotid endarterectomy with bovine pericardial patch repair which utilised BioGlue seal the patch suture line. Conclusion BioGlue...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ارومیه 1377

the methods which are used to analyze microstrip antennas, are divited into three categories: empirical methods, semi-empirical methods and full-wave analysis. empirical and semi-empirical methods are generally based on some fundamental simplifying assumptions about quality of surface current distribution and substrate thickness. thses simplificatioms cause low accuracy in field evaluation. ful...

2013
Iris Starnberger Dennis Poth Pardha Saradhi Peram Stefan Schulz Miguel Vences Jette Knudsen Michael F Barej Mark-Oliver Rödel Manfred Walzl Walter Hödl

Males of all reed frog species (Anura: Hyperoliidae) have a prominent, often colourful, gular patch on their vocal sac, which is particularly conspicuous once the vocal sac is inflated. Although the presence, shape, and form of the gular patch are well-known diagnostic characters for these frogs, its function remains unknown. By integrating biochemical and histological methods, we found strong ...

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