A hemagglutination-inhibition test for the determination of vaccinia antibodies in serum was first described by Nagler.5 It has been used extensively by us in a standardized form.2 Collier8 has utilized a modification of the method in his study of adults. The present report deals with the determination of the titre of vaccinia antibodies in the sera of 182 mothers at term and in the cord blood ...

A series of 6 chimpanzees was inoculated orally with stool from a poliomyelitis patient. Three of these animals had been given 170 cc. of homologous, hyperimmune monkey serum prior to inoculation, while three were unprotected. All 6 of the animals were subsequently shown to have poliomyelitis virus in their stools and characteristic lesions in their central nervous systems although none of them...

In a previous paper (Hirose et al., 1962) it was reported that guinea pigs highly immunized against a bacterial suspension of Corynebacterium diphtheriae resisted to a challenge by the conjunctival method (Murata et al., 1959) with a toxinogenic virulent strain without even traces of antitoxic immunity, while a passive transfer of the immunity failed. The reason for this failure may have been d...

BACKGROUND The use of bovine in vitro embryo production (IVP) increases the reproductive potential of genetically superior cows, enabling a larger scale of embryo production when compared with other biotechnologies. However, deleterious effects such as abnormal fetal growth, longer gestation period, increased birth weight, abortion, preterm birth and higher rates of neonatal mortality have been...

Neonates are severely compromised in the ability to generate an immune response to pathogens and thus rely heavily on maternally derived immunity that is acquired by transplacental and transmammary means. The passive transfer of maternal herpes simplex virus (HSV)-specific antibody is critical in determining the outcome of neonatal HSV infection. In adults, psychological stress alters immune re...