نتایج جستجو برای: parthenotes

تعداد نتایج: 74  

Journal: :Endangered Species Research 2023

The zebra shark Stegostoma tigrinum , a popular aquarium fish, is an endangered species that known to readily reproduce both sexually and through facultative parthenogenesis while in human care. Artificial insemination trials took place between 2011 2013 resulted the hatching of 2 produced (herein heterozygotes) 10 parthenogenetic sharks allowed for retrospective comparison growth, feeding long...

Journal: :The Japanese journal of veterinary research 2003
Mario A Martinez Diaz Masami Suzuki Masumi Kagawa Koji Ikeda Yoshiyuki Takahashi

This study aimed to verify the beneficial effect of cycloheximide (CHX) treatment on the development of porcine somatic cell nuclear transfer (NT) embryos, which were constructed with enucleated oocytes and cumulus cells by using a single direct current (DC) pulse. In the first experiment, a single DC pulse applied to the induction of fusion and activation of NT embryos gave a high fusion rate....

2015
Jae Yeon HWANG Kwang-Hwan CHOI Dong-Kyung LEE Seung-Hun KIM Eun Bae KIM Sang-Hwan HYUN Chang-Kyu LEE

X-chromosome inactivation (XCI) is an epigenetic process that equalizes expression of X-borne genes between male and female eutherians. This process is observed in early eutherian embryo development in a species-specific manner. Until recently, various pluripotent factors have been suggested to regulate the process of XCI by repressing XIST expression, which is the master inducer for XCI. Recen...

Journal: :American journal of physiology. Endocrinology and metabolism 2008
Zhiming Han Rita Vassena Maggie M Y Chi Santhi Potireddy Miriam Sutovsky Kelle H Moley Peter Sutovsky Keith E Latham

Cloned mouse embryos display a marked preference for glucose-containing culture medium, with enhanced development to the blastocyst stage in glucose-containing medium attributable mainly to an early beneficial effect during the first cell cycle. This early beneficial effect of glucose is not displayed by parthenogenetic, fertilized, or tetraploid nuclear transfer control embryos, indicating tha...

Journal: :Molecular reproduction and development 2005
Kyu-Chan Hwang Hwa-Young Lee Xiang-Shun Cui Jin-Hoi Kim Nam Hyung Kim

Successful embryonic development is dependent on the temporal and stage-specific expression of appropriate genes. Currently, information on specific gene expression during early cleavage-stage embryos before zygotic gene activation (ZGA) is limited. In the present study, we compare gene expression between porcine 2-cell and blastocyst stage parthenotes to identify genes that are specifically or...

2016
Jeongwoo Kwon Sung-min Jeong Inchul Choi Nam-Hyung Kim

ADAM10 (A Disintegrin and Metalloprotease domain-containing protein 10) is a cell surface protein with a unique structure possessing both potential adhesion and protease domains. However, the role of ADAM10 in preimplantation stage embryos is not clear. In this study, we examined the expression patterns and functional roles of ADAM10 in porcine parthenotes during preimplantation development. Th...

2012
Carmen Naturil-Alfonso María dels Desamparats Saenz-de-Juano David S. Peñaranda José S. Vicente Francisco Marco-Jiménez

Parthenogenetic embryos are one attractive alternative as a source of embryonic stem cells, although many aspects related to the biology of parthenogenetic embryos and parthenogenetically derived cell lines still need to be elucidated. The present work was conducted to investigate the gene expression profile of rabbit parthenote embryos cultured under in vivo conditions using microarray analysi...

Journal: :The Journal of clinical investigation 2013
Michael Didié Peter Christalla Michael Rubart Vijayakumar Muppala Stephan Döker Bernhard Unsöld Ali El-Armouche Thomas Rau Thomas Eschenhagen Alexander P Schwoerer Heimo Ehmke Udo Schumacher Sigrid Fuchs Claudia Lange Alexander Becker Wen Tao John A Scherschel Mark H Soonpaa Tao Yang Qiong Lin Martin Zenke Dong-Wook Han Hans R Schöler Cornelia Rudolph Doris Steinemann Brigitte Schlegelberger Steve Kattman Alec Witty Gordon Keller Loren J Field Wolfram-Hubertus Zimmermann

Uniparental parthenotes are considered an unwanted byproduct of in vitro fertilization. In utero parthenote development is severely compromised by defective organogenesis and in particular by defective cardiogenesis. Although developmentally compromised, apparently pluripotent stem cells can be derived from parthenogenetic blastocysts. Here we hypothesized that nonembryonic parthenogenetic stem...

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