The R1 plasmid employs ATP-driven polymerisation of the actin-like protein ParM to move newly replicated DNA to opposite poles of a bacterial cell. This process is essential for ensuring accurate segregation of the low-copy number plasmid and is the best characterised example of DNA partitioning in prokaryotes. In vivo, ParM only forms long filaments when capped at both ends by attachment to a ...

Dany Garant,* Ian A. Fleming,* Sigurd Einum* and Louis Bernatchez Département de Biologie, Université Laval, Ste-Foy, Québec, Canada Coastal Oregon Marine Experiment Station and Department of Fisheries and Wildlife, Oregon State University, Hatfield Marine Science Center, Newport, OR, USA Norwegian Institute for Nature Research (NINA), Trondheim, Norway Correspondence and present address: Dany ...

The [3+2] cycloaddition reaction of N-aryl-C-carbamoylnitrone (nitrone 1) with N-arylitaconimide (ethylene 2) was computationally studied using the B3LYP/6-31G(d) level theory. An analysis different energetic profiles and transition states’ optimized structures clearly indicated that this 32CA occurred through a non-polar, asynchronous, one-step mechanism, favoring formation ortho–endo cycloadd...

A pyridylpyrazole bearing a hydroxyethyl substituent group has been synthesized by condensation of (Z)-4-hydroxy-4-(pyridin-2-yl)but-3-en-2-one with 2-hydroxyethylhydrazine. The compound was well characterized and its structure confirmed by single crystal X-ray diffraction. Density functional calculations have been performed using DFT method with 6-31G* basis set. The HOMO-LUMO energy gap, bind...

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