Echoviruses have been implicated in multiple human disease syndromes, including aseptic meningitis, paralysis, and heart disease, but no animal model is available for studying the pathogenesis of infection. Production of human integrin very late antigen 2, a receptor for echovirus type 1, in transgenic mice conferred susceptibility to viral infection. Intracerebral inoculation of newborn transg...

Thyrotoxic periodic paralysis (TPP) is characterized by recurrent episodes of muscle weakness and hypokalemia associated with thyroid hyperactivity. Reported predominantly among individuals of Asian descent, TPP is a rare manifestation of hyperthyroidism in western populations. We describe a typical case of TPP in a 33-year-old portuguese male, who presented with acute tetraparesis associated w...

In 19-26% of patients hospitalized with suspected stroke, the cause neurological symptoms are not cerebrovascular diseases. this case newly diagnosed thyrotoxic periodic paralysis we presented clinical, laboratory and instrumental features disease. The search for allowed to identify an endocrinological disease - diffuse toxic goiter, prescribe antithyroid therapy. data prospective patient obser...

BACKGROUND Diseases that cause acute flaccid paralysis (AFP) often progress rapidly, thus may cause life threatening complications, therefore, their diagnosis and cure are important. This study was carried out to investigate the causes of acute generalized weakness in children referred to Amirkola Children's Hospital, in Babol, Iran. METHODS In this case series, the epidemiological causes of ...

Guillain-Barré is one of the most common syndromes causing acute flaccid paralysis worldwide, usually starting with a motor component and spreading upwards; organism this pathology Campylobacter Jejuni. However, due to pandemic, presence neurological has been reported in patients SARS-CoV2. The process by which disease produced interaction between immunological processes activation autoantibodi...

The Guillain Barre Syndrome (GBS) is an acute immune mediated progressive polyneuropathy having monophasic illness leading to paralysis. clinical features are ascending symmetrical muscle weakness that may lead respiratory failure. Diagnosis based upon presentation and supported by a lumbar puncture with CSF analysis demonstrating albumin cytological dissociation electrophysiological studies. O...

West Nile virus (WNV) is one of the leading causes of insect-borne encephalitis and acute flaccid paralysis in the US. Acute flaccid paralysis is a potentially serious illness, which manifests itself as a Guillain-Barré-like syndrome with generalized weakness and shortness of breath. We report a case involving a patient who presented with acute flaccid paralysis due to WNV infection and was suc...

Acquired peripheral facial nerve paralysis is a relatively common disorder that affects both children and adults. The most frequent nontrauma-related etiologies in otherwise neurologically intact patients are idiopathic (Bell's palsy) and infectious, which includes otitis media, herpes zoster, Lyme disease, herpes simplex virus, Epstein-Barr virus, and Mycoplasma pneumoniae. Cat scratch disease...

Sickle cell anemia is a disease caused by production of abnormal hemoglobin. Infection, acute splenic sequestration crisis, aplastic crises, acute chest syndrome, stroke, cholelithiasis, renal disease and pain are the major complications. Unilateral or bilateral diaphragm paralysis maybe seen following phrenic nerve injury and with a variety of motor-neuron diseases, myelopathies, neuropathies,...

Botulism is the acute, flaccid paralysis caused by a neurotoxin produced by Clostridium botulinum. In the infant, clinical symptoms are usually unspecific such as poor feeding, weak suck, feeble cry, drooling, followed by a symmetric, descending, flaccid paralysis beginning with the cranial nerve musculature. The initial symptoms of the disease are often similar to several diseases and therefor...