Greyish-white spots, varying in size, caused diagnostic problems in 2 patients with pre-invasive corneal carcinoma. Keratectomy specimens permitting light and electron microscopy indicated that the smaller spots predominating in one patient correlated with epithelial microcysts and vacuoles, while areas of parakeratosis accounted for the macroscopic white patches found in the other. A variety o...

Figure 1. A, Well-demarcated exophytic fungating plaque with linear keloid, peripheral crusting, and distal hyperpigmentation; B, hematoxylin-eosin stain reveals parakeratosis, pseudoepitheliomatous hyperplasia, mixed inflammatory infiltrate, and foreign body giant cells (courtesy of M. J. Zimarowski);C, hematoxylin-eosin stain of pigmented sclerotic bodies (arrow) (courtesy of M. J. Zimarowski...

Congenital foot abnormalities such as syndactyly, polydactyly, and brachymetatarsia are commonly seen by plastic surgeons. There have been reports of cases of congenital synostosis of the foot, with the majority of cases involving the rear foot and midfoot Fig. 2. (A) Cross-section of the giant cutaneous horns (GCH) showing hollowing of conical component with surrounding parakeratosis, calcific...

Background & Objectives:  Accurate differentiation of eczema and psoriasis can be difficult, especially in areas of palm and sole. This study was designed to evaluate histopathological features and identify statistically significant parameters in distinguishing palmoplantar psoriasis from eczema of these regions in patients referring to Razi Skin Hospital, Tehran, Iran. Methods: In a cross-sec...

We present a case of hyperkeratosis lenticularis perstans (Flegel's disease) in a 71-year-old-woman. Apart from all the typical morphological features of the disease, we evidenced mounds of parakeratosis that contained neutrophils, alternating with other strata of the horny layers in which no infiltrate was seen. Such a pattern has been described in association with diseases that show a periodi...

A 3-month-old short haired pointer with crusty local alopecia around the eyes was presented to SmallAnimal Hospital of Tehran University. Scraping and biopsy were obtained from lesions of affected area.Notoedres sp. was diagnosed in skin scraping by parasitologic examination. Furthermore, histopathology oflesions demonstrated moderate hyperplastic epidermis, parakeratosis and acanthosis.

Background & Objectives: Accurate differentiation of eczema and psoriasis can be difficult, especially in areas of palm and sole. This study was designed to evaluate histopathological features and identify statistically significant parameters in distinguishing palmoplantar psoriasis from eczema of these regions in patients referring to Razi Skin Hospital, Tehran, Iran. Methods: In a cross-secti...

The largest and most vital part of the human body is skin any change in features termed as a lesion. paper considers granular parakeratosis lesion that an epidermal reaction occurring due to disorder keratinization, mainly seen intertriginous areas. manual inspection bit cumbersome which automated system proposed this paper. main goal determine size depth lesions using ensemble algorithm, parti...

Psoriasis is defined as a common, genetically determined, inflammatory and proliferative disease of skin, the most characteristic lesions consisting of chronic, sharply demarcated, dull-red, scaly plaques, particularly on the extensor prominences and in the scalp. The prevalence of Psoriasis in Western Europe and Scandinavia is between about 1.5 and 3%. The low prevalence of Psoriasis in orient...