INTRODUCTION In an effort to treat obesity, health care professionals pursue, by means of dieting and exercise interventions, weight loss as a primary goal of treatment. Although in few cases these interventions induce shortterm moderate weight loss, in the long-term, the efficacy of these treatments is at least questionable. Weight-loss interventions based on restrictive diets may be associate...

The current radiation safety paradigm using the linear no-threshold (LNT) model is based on the premise that even the smallest amount of radiation may cause mutations increasing the risk of cancer. Autopsy studies have shown that the presence of cancer cells is not a decisive factor in the occurrence of clinical cancer. On the other hand, suppression of immune system more than doubles the cance...

V ascular comorbidities and complications are the major causes of excessive mortality and costs in patients with diabetes (1,2). For more than half a century, overwhelming evidence has been accumulating that demonstrates significant harmful effects of hyperglycemia. As shown in the Multiple Risk Factor Intervention Trial (MRFIT) study, at any given level of major cardiovascular risk factors, di...

The treatment of diseases has been based on the concept of homeostasis and has not incorporated an understanding of biologic rhythms and their underlying mechanisms. Biologic rhythms are implicated in cardiovascular events. Failure to recognize the circadian decline in blood pressure may result in iatrogenic chronopathological events, including anterior ischemic optic neuropathy and cerebrovasc...

ankind has the right to avail the best that is available in any system of medicine. The proposition of cause and effect relationship by Lister in the 19 century laid the foundation of modern medicine and brought about a revolution in the diagnosis and treatment of diseases. With the advent of antibiotics, diagnostics, asepsis and surgery, emerged a period where the cure of disease and the impro...

In this work, a method for generating external schemas in object oriented databases in the ODMG framework is proposed. External schema generation involves obtaining all the relationships existing between the classes selected to make up an external schema. This generation process is part of an external schema definition system that we are developing, which allows the definition of external schem...

The evidence on early childhood strongly suggests the need to shift child health policy from the current focus on social welfare to a socio-ecologically based approach. This paper reviews three governing instruments, exhortation, expenditure and regulation, that have been used by governments in Australia and discusses the relative effectiveness of these approaches in shifting the child health p...

Recent evidence suggests that testosterone replacement therapy after prostate cancer treatment may be safer than previously thought. The authors review the basis for the common dilemma as to how to approach the treatment of testosterone deficiency after successful treatment for prostate cancer, and explain how the paradigm is shifting as our knowledge of androgen physiology grows. ROBERT M. COW...