PURPOSE. To examine the biomechanical deformation of load bearing structures of the optic nerve head (ONH) resulting from raised intracranial pressure, using high definition optical coherence tomography (HD-OCT). The authors postulate that elevated intracranial pressure induces forces in the retrolaminar subarachnoid space that can deform ONH structures, particularly the peripapillary Bruch's m...

This is the first report of an experimental intraorbital ligature producing papilledema characterized by axonal swelling and accumulation of mitochondria in the lamina retinalis of the optic disc of rhesus monkeys subjected to immediately retrobulbar ligature of a portion of the optic nerve. This is an improved technique for investigating the pathogenesis of papilledema and optic neuropathy.

PURPOSE Geometric morphometrics (GM) was used to analyze the shape of the peripapillary retinal pigment epithelium-Bruch's membrane (RPE/BM) layer imaged on the SD-OCT 5-line raster in normal subjects and in patients with papilledema and ischemic optic neuropathy. METHODS Three groups of subjects were compared: 30 normals, 20 with anterior ischemic optic neuropathy (AION), and 25 with papille...

purpose: to report a case of spinal cord tumor with visual symptoms and papilledema due to increased intracranial pressure. patient and findings: a 24-year-old woman was referred because of recent blurred vision in both eyes. visual acuity was 20/25 and 20/20 in the right and left eyes, respectively. fundoscopy revealed bilateral papilledema. other ophthalmic examinations were normal. visual fi...

Background: Paroxysmal movements in the form of tonic spasms, dystonia, choreoathetosis and hemidyskinesia have been reported in patient with multiple sclerosis (MS). Intracranial hypertension with headache and papilledema resembling idiopathic intracranial hypertension (IIH) exceptionally occurs in patient with MS. Conversely, IIH may rarely present as movement disorder in children. Aims of th...

Sung-eun E. Kyung MD, PhD , Jonathan C. Horton MD, PhD* Department of Ophthalmology, School of Medicine, University of Dankook at Cheonan, South Korea Department of Ophthalmology, University of California, San Francisco, San Francisco, California Department of Neurology, University of California, San Francisco, San Francisco, California Department of Physiology, University of California, San Fr...

Papilledema is a syndrome of the retina in which retinal optic nerve inflated by elevation intracranial pressure. The papilledema abnormalities such as fiber layer (RNFL) opacification may lead to blindness. These could be seen through capturing images means fundus camera. This paper presents deep learning-based automated system that detects and grades U-Net Dense-Net architectures. proposed ap...

herpes simplex virus accounts for 10 to 25% of sporadic viral encephalitis throughout the world among people of different age with two peaks, one at 5 to 30 and the other at > 50 years of age. pathologic process includes focal brain tissue inflammation and necrosis (predominantly temporal lobe). therefore local neurological signs and symptoms will ensue. although csf pressure rising due to infl...