Intracranial meningiomas continue to challenge our best clinical efforts to eliminate them once discovered and deemed appropriate for treatment. Malignant meningiomas constitute 10% to 15% of all meningiomas and limited information exists regarding adjuvant treatment. The external whole brain irradiation is recommended. Traditional chemotherapy has proven ineffective; thus, new chemotherapeutic...

OBJECTIVE Malignant meningiomas are rare and have worse prognosis than benign meningiomas. We report our experience of a malignant meningioma and review relevant literature in an attempt to investigate the clinical features, treatment, and prognosis of these tumors. METHODS Fifteen patients underwent surgical treatment for intracranial malignant meningiomas between year 1990 and 2012 in our i...

The presence of five discrete synchronous or metachronous primary neoplasms in a single patient is an extremely rare event. This is a report of a patient with a malignant (invasive) thymoma and four other independent primary neoplasms including: gliosarcoma, papillary thyroid cancer, meningioma and metastatic adenocarcinoma of the colon, found synchronously at autopsy. Thymoma patients appear t...

conclusions primary extracranial meningiomas (pems) without intracranial origin are very rare and because of their slow growing nature are initially managed by primary care physicians. case presentation we report a case of slowly progressing extracranial meningioma that was presented in a young adult woman. the tumor was asymptomatic but large enough to cause cosmetic discomfort. patient underw...

meningioma is usually a benign central nervous system (cns) tumor. metastasis is rare; however if it does occur the most metastatic sites are the liver and lungs. here, two cases of cns meningioma with metastasis to cervical lymph nodes are reported. the first case, a 48 year-old man developed cervical lymph node metastasis nine years after primary tumor diagnosis. the second case, a 23 year-ol...

OBJECTIVE To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS Immunohistochemistry staining was performed on samples from patients with meningioma. The results were graded according to the positive ratio and intensity of tissue immunoreactivity. The expression of E-cadherin and beta-catenin in meningioma was analyzed by its relationship with WHO2007...

Meningiomas and neurofibromas are the most common extramedullary tumors in the region of the foramen magnum. The clinical symptoms are variable, including headache, occipitocervical pain, and hoarseness. Neurological symptoms are present only in 40% of cases. The age group ranges from 4 to 56 years. A number of patients are misdiagnosed as multiple sclerosis, syringomyelia, and cervical disc di...

Thyroid cancer accounts for approximately 1% of all human cancers. Follicular carcinoma thyroid (FCT) is the second most common thyroid cancer after papillary carcinoma. Follicular carcinoma thyroid accounts for 10-15% of clinically evident thyroid malignancies. Follicular carcinoma thyroid commonly metastasize to lung and bone. Intracranial metastasis occurs in about only 1%. Follicular carcin...