نتایج جستجو برای: p005 effect58

تعداد نتایج: 76  

Journal: :Mechanisms of Development 2009
Julien Bouissac Naoko Yoshioka Shin-Ichi Nishikawa

Gonadotropin releasing hormone (GnRH) is a multifunctional decapeptide that possess endocrine as well as neuromodulatory roles and is present in all vertebrates. Endocrine GnRH cells play a crucial role in the establishment of the hypothalamic–pituitary– gonadal axis in many species. Recent studies have found that the prokineticin2 (pk2) and prokineticin receptor2 (pkr2) genes are involved in t...

Journal: :Mechanisms of Development 2009
Noriko Osumi Miho Matsumata Nobuyuki Sakayori Motoko Maekawa Takeo Yoshikawa Yuji Owada Masanori Kontani Hiroshi Kawashima Yoshinobu Kiso

nature of Hex+Cxcr4+ (H+C+) ES cell derived ADE. Global expression analysis of ES cell derived ADE lead to the identification of an H+C+ gene expression cluster that contains well know anterior endoderm markers alongside a novel set of new sequence tags. Based on multiple pairwise comparisons between the H+C+ fraction and both differentiated and undifferentiated ES cell fractions, 66 genes were...

Journal: :Mechanisms of Development 2009
Jeannine Witte Otto Baumann

manipulating spindle by laser, we showed that the spindle asymmetry is essential for asymmetric nuclear localization of b-catenin. Because a kinesin inhibitor disrupted asymmetry of b-catenin localization, we propose that kinesin dependent transport of b-catenin along astral microtubules causes the enhancement of nuclear b-catenin export. This process occurs more efficiently in the anterior sid...

Journal: :Mechanisms of Development 2009
Adam Prickett Ruth B. McCole Reiner Schulz Rebecca J. Oakey

Dopa Decarboxylase (Ddc) is an enzyme that plays a fundamental role in the biosynthesis of catecholamine neurotransmitters and serotonin. A short form transcriptional variant of Ddc called Ddc_exon1a which originates from an alternative promoter at exon 1a, is highly expressed in the trabecular cardiomyocytes during development of pre-natal heart and is progressively silenced during post natal ...

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