We investigated the effect of dietary conjugated linoleic acid (CLA) along with n-3 polyunsaturated fatty acid (n-3 PUFA) on yolk fatty acid composition and volatile compounds in eggs that were raw (RA), hard-boiled (HB), or hard-boiled, irradiated (HBI, 2.5 kGy). Single Comb White Leghorn laying hens (n = 40) were randomly assigned to one of the four experimental diets containing 0, 0.5, 1.0, ...

The association between HLA-DR4 and rheumatoid arthritis (RA) has been established in many ethnic groups. To clarify the determinant of susceptibility to RA, a polymorphic segment of the HLA-DRB gene was amplified in vitro by polymerase chain reaction and analyzed with oligonucleotide probes specific for the HLA-DR4 DNA sequences. A particular sequence encoding amino acids Gln70-Arg71-Arg72-Ala...

Female Sprague-Dawley rats were treated at 50 and 57 days of age with 2.5 mg per 100 g body weight of A/-methyl-A/nitrosourea (MNU). At 60 days of age, the animals were divided into eight groups (40 rats/group) and treated as follows: (a) controls; (b) immune stimulation (IS); (c) hormone inhibition (HI); (d) HI + IS; (e) retinyl acetate feeding (RA); (f ) RA + IS; (g) RA + HI; and (h) RA + HI ...

the recovery and removal of the most organic acids in liquid solutions is usually treated with fixed-bed adsorption processes. among many adsorbents, granular activated carbon (gac) is used to remove organic pollutants such as benzoic acid (ba) from wastewaters conventionally. in this research, adsorption isotherm curves of ba onto gac at varying temperatures 25-60 °c are developed and the amou...

OBJECTIVES To investigate the role of potential immunoselected phages displaying random peptides in addition to possible antigen leads in rheumatoid arthritis (RA) by assaying the levels of synovial fluid (SF) and serum antibodies to synthetic peptides. METHODS Serum and SF antibodies from patients and controls were measured using an enzyme linked immunosorbent assay (ELISA). RESULTS Sera a...

Alveolarization is impaired in rats treated with dexamethasone (Dex) on postnatal days 4-13, but concomitant treatment with all-trans retinoic acid (RA) increases alveolar number. To determine whether morphological changes induced by Dex and/or RA predict changes in lung function at 1 mo, we assessed resting breathing parameters, dynamic compliance, ventilation required to maintain O(2) saturat...

The incidence of rheumatoid arthritis (RA) has been increased among people who possess habit of tobacco smoking. In the present study, zinc (Zn), copper (Cu), manganese (Mn), lead (Pb) and cadmium (Cd) were determined in scalp hair samples of smokers and nonsmokers RA patients, residents of Dublin, Ireland. For comparison purposes scalp hair samples of age and sex matched healthy smokers and no...

ABSTRACT.: In the reaction of kidneys to injury, cytokine-driven proliferation plays an important role and precedes the development of glomerulosclerosis. There is great interest in agents that may interfere with such proliferation. Therefore, a rat model of mesangioproliferative glomerulonephritis (induced by anti-Thy1.1) was studied, and the effects of all-trans-retinoic acid (all-trans-RA) a...

Treatment of HL-60 cells, a human promyelocytic leukemia cell line, with the vitamin A derivative retinoic acid (RA) for 7 days resulted in a dose-dependent decrease in proliferation and increase in granulocytic differentiation. The role of transforming growth factor-p, (TGF-p,), a protein with pleiotropic effects on the proliferation and differentiation of various cell types, was examined duri...

Neutralization with alkaline compounds is one of the most common adulterations in milk. The rosolic acid method a classical test widely used different countries for detection neutralizers official and modified version were validated single laboratory validation process considering four adulterants: sodium bicarbonate(BI), carbonate(CA), hydroxide(HY) citrate(CI). version, which presented better...